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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG10043-RA through 18771 annotations produced 1 hits



Drosophila rho-type guanine exchange factor (rtGEF):

Annotation Number : CG10043
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015803
Gbrowse : chr2L:20350435-20365261 (+) // 100.0 //
Probeset : 1639115_s_at
Accessions : protein= NP_001097184; /// NP_001097185; /// NP_001163021; /// NP_477174; /// NP_724258;, nucleotide= NM_001103714; /// NM_001103715; /// NM_001169550; /// NM_057826; /// NM_165327;
Pathway : 0005622 // intracellular // inferred from electronic annotation
Interpro : 0005085 // guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005089 //
FlyMine data for FBgn0015803.
Homophila reports that CG10043 is a close match (1e-15) to human gene ARHGEF9;KIAA0424;PEM2 (NP_056000), a gene associated with Hyperekplexia and epilepsy, 300607 (3).
BioGrid reports that CG10043 interacts with CG10295 CG11345 CG11722 CG11876 CG16728 CG2204 CG6549 CG10604 CG11738 CG11881 CG12496 CG12799 CG1307 CG14625 CG15816 CG17050 CG18659 CG31245 CG31247 CG31826 CG32156 CG3270 CG33017 CG4617 CG5140 CG6607 CG8948 CG9212 .
TRiP has 1 RNAi stocks for FBgn0015803 available for purchase.
VDRC has 4 RNAi stocks for FBgn0015803 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain118 ± 84 of 4 1.00None
Head82 ± 44 of 4 0.70Down
Eye37 ± 24 of 4 0.33Down
Thoracicoabdominal ganglion113 ± 44 of 4 1.00None
Salivary gland135 ± 84 of 4 1.19None
Crop160 ± 64 of 4 1.40Up
Midgut118 ± 74 of 4 1.00None
Tubule68 ± 34 of 4 0.60Down
Hindgut108 ± 34 of 4 0.90None
Heart106 ± 134 of 4 0.93None
Fat body56 ± 64 of 4 0.50Down
Ovary218 ± 24 of 4 1.90Up
Testis24 ± 34 of 4 0.20Down
Male accessory glands57 ± 44 of 4 0.50Down
Virgin spermatheca67 ± 64 of 4 0.59Down
Mated spermatheca72 ± 84 of 4 0.64Down
Adult carcass124 ± 64 of 4 1.10None
Larval CNS213 ± 164 of 4 1.87Up
Larval Salivary gland120 ± 124 of 4 1.05None
Larval midgut236 ± 94 of 4 2.07Up
Larval tubule89 ± 54 of 4 0.80Down
Larval hindgut189 ± 114 of 4 1.66Up
Larval fat body33 ± 24 of 4 0.30Down
Larval trachea98 ± 64 of 4 0.87Down
Larval carcass254 ± 104 of 4 2.24Up
S2 cells (growing)214 ± 84 of 4 1.88Up
Whole fly113 ± 14 of 4

Looking for CG10043-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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