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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG10052-RA through 18771 annotations produced 1 hits

Retinal Homeobox (Rx):

Annotation Number : CG10052
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0020617
Gbrowse : chr2R:16804284-16824537 (+) // 100.0 //
Probeset : 1632237_at
Accessions : protein= NP_726006;, nucleotide= NM_166413;
Pathway : DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II
Interpro : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author sta
FlyMine data for FBgn0020617.
BDGP gene expression has embryonic in situ data for Rx: 41 pix of staining in 13 body parts.
Homophila reports that CG10052 is a close match (4e-11) to human gene EMX2 (NP_004089), a gene associated with Schizencephaly, 269160 (3).
TRiP has 1 RNAi stocks for FBgn0020617 available for purchase.
VDRC has 3 RNAi stocks for FBgn0020617 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain42 44 of 410.60Up
Head6 00 of 4 1.70Up
Eye1 00 of 4 0.28Down
Thoracicoabdominal ganglion4 10 of 4 1.20None
Salivary gland7 30 of 4 1.90None
Crop1 00 of 4 0.50Down
Midgut3 10 of 4 0.80None
Tubule1 00 of 4 0.50Down
Hindgut2 00 of 4 0.50None
Heart1 00 of 4 0.33Down
Fat body5 40 of 4 1.36None
Ovary1 00 of 4 0.40Down
Testis5 10 of 4 1.40None
Male accessory glands2 10 of 4 0.50None
Virgin spermatheca0 00 of 4 0.19Down
Mated spermatheca2 00 of 4 0.64None
Adult carcass2 10 of 4 0.70None
Larval CNS40 44 of 410.21Up
Larval Salivary gland1 00 of 4 0.25Down
Larval midgut2 00 of 4 0.49None
Larval tubule4 10 of 4 1.00None
Larval hindgut1 00 of 4 0.28Down
Larval fat body4 30 of 4 1.20None
Larval trachea1 10 of 4 0.37None
Larval carcass2 10 of 4 0.67None
S2 cells (growing)1 00 of 4 0.26Down
Whole fly4 00 of 4

Looking for CG10052-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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