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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG10119-RA through 18771 annotations produced 1 hits

lamin C (LamC):

Annotation Number : CG10119
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010397
Gbrowse : chr2R:10458308-10463307 (-) // 100.0 //
Probeset : 1629981_at
Accessions : protein= NP_523742;, nucleotide= NM_079018;
Pathway : 0005634 // nucleus // inferred from electronic annotation /// 0005638 // lamin filament // inferred from sequence or str
Interpro : 0005198 // structural molecule activity // inferred from electronic annotation
FlyMine data for FBgn0010397.
BDGP gene expression has embryonic in situ data for LamC: 20 pix of staining in 11 body parts.
Homophila reports that CG10119 is a close match (3e-14) to human gene NEFH (NP_066554), a gene associated with {Amyotrophic lateral sclerosis, susceptibility to}, 105400 (3).
BioGrid reports that CG10119 interacts with CG18398 .
TRiP has 1 RNAi stocks for FBgn0010397 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain51 34 of 4 0.30Down
Head171 54 of 4 1.00None
Eye131 74 of 4 0.75None
Thoracicoabdominal ganglion119 64 of 4 0.70Down
Salivary gland211 54 of 4 1.20None
Crop793 134 of 4 4.50Up
Midgut261 204 of 4 1.50Up
Tubule350 774 of 4 2.00Up
Hindgut627 244 of 4 3.60Up
Heart167 104 of 4 0.95None
Fat body216 354 of 4 1.23None
Ovary165 44 of 4 0.90None
Testis110 34 of 4 0.60Down
Male accessory glands157 114 of 4 0.90None
Virgin spermatheca250 204 of 4 1.43Up
Mated spermatheca297 114 of 4 1.69Up
Adult carcass222 164 of 4 1.30None
Larval CNS87 194 of 4 0.50Down
Larval Salivary gland623 514 of 4 3.55Up
Larval midgut301 204 of 4 1.72Up
Larval tubule328 184 of 4 1.90Up
Larval hindgut917 244 of 4 5.22Up
Larval fat body161 94 of 4 0.90None
Larval trachea808 544 of 4 4.60Up
Larval carcass886 644 of 4 5.05Up
S2 cells (growing)24 24 of 4 0.14Down
Whole fly175 154 of 4

Looking for CG10119-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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