FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG10120-RB through 18771 annotations produced 1 hits

Malic enzyme (Men):

Annotation Number : CG10120
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0002719
Gbrowse : chr3R:8538818-8548267 (-) // 100.0 //
Probeset : 1629095_a_at
Accessions : protein= NP_524880; /// NP_731739;, nucleotide= NM_080141; /// NM_169479;
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // inferred f
FlyMine data for FBgn0002719.
BDGP gene expression has embryonic in situ data for Men: 29 pix of staining in 17 body parts.
Homophila reports that CG10120 is a close match (2e-160) to human gene ME2 (NP_002387), a gene associated with {Epilepsy, idopathic generalized, susceptibility to}, 600669 (3).
BioGrid reports that CG10120 interacts with CG13576 CG15177 CG6667 .
TRiP has 2 RNAi stocks for FBgn0002719 available for purchase.
VDRC has 1 RNAi stocks for FBgn0002719 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	456 ± 16	4 of 4	0.50	Down
Head	1514 ± 34	4 of 4	1.70	Up
Eye	868 ± 125	4 of 4	0.96	None
Thoracicoabdominal ganglion	557 ± 9	4 of 4	0.60	Down
Salivary gland	51 ± 4	2 of 4	0.06	Down
Crop	2003 ± 65	4 of 4	2.20	Up
Midgut	545 ± 29	4 of 4	0.60	Down
Tubule	1977 ± 26	4 of 4	2.20	Up
Hindgut	945 ± 26	4 of 4	1.00	None
Heart	2915 ± 153	4 of 4	3.23	Up
Fat body	3827 ± 356	4 of 4	4.24	Up
Ovary	479 ± 11	4 of 4	0.50	Down
Testis	785 ± 25	4 of 4	0.90	Down
Male accessory glands	276 ± 21	4 of 4	0.30	Down
Virgin spermatheca	4206 ± 141	4 of 4	4.65	Up
Mated spermatheca	2897 ± 223	4 of 4	3.21	Up
Adult carcass	2830 ± 77	4 of 4	3.10	Up
Larval CNS	672 ± 61	4 of 4	0.74	Down
Larval Salivary gland	24 ± 6	2 of 4	0.03	Down
Larval midgut	734 ± 86	4 of 4	0.81	None
Larval tubule	1087 ± 65	4 of 4	1.20	None
Larval hindgut	664 ± 53	4 of 4	0.74	Down
Larval fat body	440 ± 58	4 of 4	0.50	Down
Larval trachea	216 ± 31	4 of 4	0.24	Down
Larval carcass	762 ± 125	4 of 4	0.84	None
S2 cells (growing)	950 ± 15	4 of 4	1.05	None
Whole fly	903 ± 17	4 of 4

Looking for CG10120-RB. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720