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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG1019-RA through 18771 annotations produced 1 hits

Muscle-specific LIM protein at 84B (Mlp84B):

Annotation Number : CG1019
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0014863
Gbrowse : chr3R:2939777-2943453 (-) // 99.73 //
Probeset : 1639980_s_at
Accessions : protein= NP_477122; /// NP_731134;, nucleotide= NM_057774; /// NM_169173;
Pathway : 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similari
Interpro : 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred
FlyMine data for FBgn0014863.
Homophila reports that CG1019 is a close match (1e-34) to human gene CLP;CMD1M;CMH12;CRP3;CSRP3 (NP_003467), a gene associated with Cardiomyopathy, dilated, 1M, 607482 (3);Cardiomyopathy, familial hypertrophic, 12, 612124 (3).
BioGrid reports that CG1019 interacts with CG10722 CG11115 CG13501 CG17440 CG7046 CG7447 CG9572 CG10619 CG11015 CG11164 CG13830 CG41099 CG1830 CG2258 CG31624 CG31839 CG32171 CG32356 CG3319 CG4001 CG4394 CG5193 CG5708 CG7954 CG8942 CG9448 .
TRiP has 1 RNAi stocks for FBgn0014863 available for purchase.
VDRC has 3 RNAi stocks for FBgn0014863 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain63 24 of 4 0.10Down
Head739 654 of 4 0.90None
Eye113 144 of 4 0.13Down
Thoracicoabdominal ganglion55 104 of 4 0.10Down
Salivary gland9 20 of 4 0.01Down
Crop1971 424 of 4 2.30Up
Midgut388 24 of 4 0.50Down
Tubule68 64 of 4 0.10Down
Hindgut1606 244 of 4 1.90Up
Heart1128 934 of 4 1.33None
Fat body68 184 of 4 0.08Down
Ovary15 34 of 4 0.00Down
Testis111 44 of 4 0.10Down
Male accessory glands1032 264 of 4 1.20Up
Virgin spermatheca58 74 of 4 0.07Down
Mated spermatheca137 134 of 4 0.16Down
Adult carcass2495 924 of 4 2.90Up
Larval CNS15 24 of 4 0.02Down
Larval Salivary gland10 30 of 4 0.01Down
Larval midgut288 94 of 4 0.34Down
Larval tubule34 34 of 4 0.00Down
Larval hindgut1429 844 of 4 1.68Up
Larval fat body9 21 of 4 0.00Down
Larval trachea170 884 of 4 0.20Down
Larval carcass3563 2034 of 4 4.20Up
S2 cells (growing)3 10 of 4 0.00Down
Whole fly849 104 of 4

Looking for CG1019-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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