FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG10240-RA through 18771 annotations produced 1 hits

Cytochrome P450 related BF6-2 (Cyp6a22):

Annotation Number : CG10240
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0013773
Gbrowse : chr2R:10759196-10760976 (+) // 100.0 //
Probeset : 1631533_at
Accessions : protein= NP_652075;, nucleotide= NM_143818;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0013773.
BDGP gene expression has embryonic in situ data for Cyp6a22: 8 pix of staining in 1 body parts.
Homophila reports that CG10240 is a close match (4e-11) to human gene CPD6;CYP2D6;P450DB1 (NP_001020332), a gene associated with Codeine sensitivity (3);Debrisoquine sensitivity (3);{?Parkinsonism, susceptibility to} (1).
BioGrid reports that CG10240 interacts with CG1151 .
VDRC has 2 RNAi stocks for FBgn0013773 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	11 ± 2	3 of 4	0.10	Down
Head	73 ± 1	4 of 4	0.70	Down
Eye	23 ± 1	4 of 4	0.21	Down
Thoracicoabdominal ganglion	3 ± 0	0 of 4	0.00	Down
Salivary gland	16 ± 2	0 of 4	0.15	Down
Crop	15 ± 1	4 of 4	0.10	Down
Midgut	6 ± 1	0 of 4	0.10	Down
Tubule	613 ± 25	4 of 4	5.50	Up
Hindgut	23 ± 1	4 of 4	0.20	Down
Heart	92 ± 7	4 of 4	0.83	None
Fat body	180 ± 32	4 of 4	1.63	Up
Ovary	238 ± 5	4 of 4	2.20	Up
Testis	6 ± 0	2 of 4	0.10	Down
Male accessory glands	31 ± 3	4 of 4	0.30	Down
Virgin spermatheca	130 ± 5	4 of 4	1.18	Up
Mated spermatheca	98 ± 5	4 of 4	0.89	None
Adult carcass	95 ± 6	4 of 4	0.90	None
Larval CNS	1 ± 1	0 of 4	0.02	Down
Larval Salivary gland	2 ± 0	0 of 4	0.02	Down
Larval midgut	3 ± 1	0 of 4	0.03	Down
Larval tubule	73 ± 4	4 of 4	0.70	Down
Larval hindgut	6 ± 1	0 of 4	0.06	Down
Larval fat body	77 ± 9	4 of 4	0.70	Down
Larval trachea	4 ± 2	1 of 4	0.04	Down
Larval carcass	4 ± 1	1 of 4	0.04	Down
S2 cells (growing)	39 ± 1	4 of 4	0.36	Down
Whole fly	110 ± 5	4 of 4

Looking for CG10240-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720