FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG10242-RA through 18771 annotations produced 1 hits

Cyp6a23 (Cyp6a23):

Annotation Number : CG10242
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033978
Gbrowse : chr2R:10763337-10765159 (+) // 100.0 //
Probeset : 1624101_at
Accessions : protein= NP_611000;, nucleotide= NM_137156;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0033978.
Homophila reports that CG10242 is a close match (2e-11) to human gene CYP11B2 (NP_000489), a gene associated with Aldosterone to renin ratio raised (3);Hypoaldosteronism, congenital, due to CMO I deficiency, 203400 (3);Hypoaldosteronism, congenital, due to CMO II deficiency, 610600 (3);{Low renin hypertension, susceptibility to} (3).
BioGrid reports that CG10242 interacts with CG16947 CG8316 .
VDRC has 4 RNAi stocks for FBgn0033978 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	28 ± 1	4 of 4	0.10	Down
Head	283 ± 20	4 of 4	0.80	None
Eye	118 ± 8	4 of 4	0.34	None
Thoracicoabdominal ganglion	23 ± 1	4 of 4	0.10	Down
Salivary gland	104 ± 10	4 of 4	0.30	Down
Crop	1304 ± 129	4 of 4	3.70	Up
Midgut	3189 ± 200	4 of 4	9.10	Up
Tubule	2894 ± 246	4 of 4	8.30	Up
Hindgut	827 ± 24	4 of 4	2.40	Up
Heart	404 ± 6	4 of 4	1.15	None
Fat body	784 ± 81	4 of 4	2.24	Up
Ovary	30 ± 0	4 of 4	0.10	Down
Testis	36 ± 2	4 of 4	0.10	Down
Male accessory glands	265 ± 37	4 of 4	0.80	None
Virgin spermatheca	1417 ± 156	4 of 4	4.04	Up
Mated spermatheca	1242 ± 41	4 of 4	3.54	Up
Adult carcass	397 ± 27	4 of 4	1.10	None
Larval CNS	10 ± 9	3 of 4	0.03	Down
Larval Salivary gland	50 ± 6	4 of 4	0.14	Down
Larval midgut	3277 ± 17	4 of 4	9.35	Up
Larval tubule	2153 ± 210	4 of 4	6.10	Up
Larval hindgut	388 ± 16	4 of 4	1.11	None
Larval fat body	184 ± 67	4 of 4	0.50	None
Larval trachea	188 ± 52	4 of 4	0.54	None
Larval carcass	212 ± 15	4 of 4	0.61	None
S2 cells (growing)	73 ± 4	4 of 4	0.21	Down
Whole fly	350 ± 77	4 of 4

Looking for CG10242-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720