FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG10247-RA through 18771 annotations produced 1 hits

Cyp6a21 (Cyp6a21):

Annotation Number : CG10247
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033981
Gbrowse : chr2R:10772766-10774456 (-) // 100.0 //
Probeset : 1624939_at
Accessions : protein= NP_611003;, nucleotide= NM_137159;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0033981.
BDGP gene expression has embryonic in situ data for Cyp6a21: 4 pix of staining in 1 body parts.
Homophila reports that CG10247 is a close match (5e-11) to human gene CPD6;CYP2D6;P450DB1 (NP_001020332), a gene associated with Codeine sensitivity (3);Debrisoquine sensitivity (3);{?Parkinsonism, susceptibility to} (1).
VDRC has 3 RNAi stocks for FBgn0033981 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	2 ± 1	1 of 4	0.10	Down
Head	113 ± 14	4 of 4	2.30	Up
Eye	48 ± 5	4 of 4	0.97	None
Thoracicoabdominal ganglion	5 ± 1	2 of 4	0.10	Down
Salivary gland	15 ± 2	1 of 4	0.31	Down
Crop	18 ± 1	4 of 4	0.40	Down
Midgut	951 ± 59	4 of 4	18.90	Up
Tubule	251 ± 28	4 of 4	5.00	Up
Hindgut	232 ± 19	4 of 4	4.60	Up
Heart	17 ± 1	4 of 4	0.36	Down
Fat body	54 ± 8	4 of 4	1.08	None
Ovary	1 ± 0	0 of 4	0.00	Down
Testis	5 ± 1	3 of 4	0.10	Down
Male accessory glands	7 ± 2	1 of 4	0.20	Down
Virgin spermatheca	37 ± 4	4 of 4	0.74	None
Mated spermatheca	19 ± 1	4 of 4	0.38	Down
Adult carcass	126 ± 9	4 of 4	2.50	Up
Larval CNS	2 ± 0	2 of 4	0.05	Down
Larval Salivary gland	2 ± 0	0 of 4	0.05	Down
Larval midgut	499 ± 24	4 of 4	9.90	Up
Larval tubule	148 ± 7	4 of 4	2.90	Up
Larval hindgut	98 ± 15	4 of 4	1.94	None
Larval fat body	233 ± 30	4 of 4	4.60	Up
Larval trachea	6 ± 1	1 of 4	0.13	Down
Larval carcass	58 ± 11	4 of 4	1.15	None
S2 cells (growing)	3 ± 0	2 of 4	0.08	Down
Whole fly	50 ± 9	4 of 4

Looking for CG10247-RA. 1 entries matched from 18771, in 0 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720