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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG10248-RA through 18771 annotations produced 1 hits



cytochrome P450 related AF5 (Cyp6a8):

Annotation Number : CG10248
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0013772
Gbrowse : chr2R:10774672-10776514 (-) // 100.0 //
Probeset : 1640755_at
Accessions : protein= NP_523749;, nucleotide= NM_079025;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0013772.
BDGP gene expression has embryonic in situ data for Cyp6a8: 21 pix of staining in 2 body parts.
Homophila reports that CG10248 is a close match (5e-12) to human gene CYP11A;P450SCC (NP_001093243), a gene associated with Adrenal insufficiency, congenital with or without 46, XY sex reversal (3);Lipoid congenital adrenal hyperplasia, 201710 (3).
VDRC has 2 RNAi stocks for FBgn0013772 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain9 ± 02 of 4 0.10Down
Head260 ± 214 of 4 2.40Up
Eye136 ± 454 of 4 1.24None
Thoracicoabdominal ganglion8 ± 20 of 4 0.10Down
Salivary gland7 ± 30 of 4 0.07Down
Crop2613 ± 824 of 423.80Up
Midgut59 ± 84 of 4 0.50Down
Tubule3140 ± 3044 of 428.50Up
Hindgut858 ± 784 of 4 7.80Up
Heart199 ± 64 of 4 1.81Up
Fat body339 ± 1784 of 4 3.09None
Ovary4 ± 10 of 4 0.00Down
Testis6 ± 10 of 4 0.10Down
Male accessory glands5 ± 20 of 4 0.10Down
Virgin spermatheca183 ± 254 of 4 1.66None
Mated spermatheca63 ± 154 of 4 0.57None
Adult carcass312 ± 484 of 4 2.80Up
Larval CNS2 ± 00 of 4 0.02Down
Larval Salivary gland7 ± 10 of 4 0.06Down
Larval midgut27 ± 34 of 4 0.25Down
Larval tubule667 ± 904 of 4 6.10Up
Larval hindgut57 ± 64 of 4 0.53Down
Larval fat body39 ± 104 of 4 0.40Down
Larval trachea5 ± 21 of 4 0.05Down
Larval carcass6 ± 20 of 4 0.06Down
S2 cells (growing)48 ± 54 of 4 0.44Down
Whole fly110 ± 44 of 4

Looking for CG10248-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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