FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG1031-RA through 18771 annotations produced 1 hits

fragment A (alpha-Est1):

Annotation Number : CG1031
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015568
Gbrowse : chr3R:3371448-3374844 (-) // 100.0 //
Probeset : 1623885_at
Accessions : protein= NP_524269;, nucleotide= NM_079545;
Interpro : 0004091 // carboxylesterase activity // inferred from sequence or structural similarity /// 0004091 // carboxylesterase
FlyMine data for FBgn0015568.
BDGP gene expression has embryonic in situ data for alpha-Est1: 13 pix of staining in 6 body parts.
Homophila reports that CG1031 is a close match (4e-18) to human gene AITD3;TG (NP_003226), a gene associated with Goiter, adolescent multinodular (1);Goiter, nonendemic, simple (3);Hypothyroidism, hereditary congenital (3);{Autoimmune thyroid disease, susceptibility to 3}, 608175 (3).
VDRC has 2 RNAi stocks for FBgn0015568 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	9 ± 0	4 of 4	0.10	Down
Head	358 ± 24	4 of 4	2.40	Up
Eye	140 ± 12	4 of 4	0.95	None
Thoracicoabdominal ganglion	13 ± 2	3 of 4	0.10	Down
Salivary gland	10 ± 2	0 of 4	0.07	Down
Crop	6 ± 0	1 of 4	0.00	Down
Midgut	248 ± 8	4 of 4	1.70	Up
Tubule	39 ± 2	4 of 4	0.30	Down
Hindgut	36 ± 5	4 of 4	0.20	Down
Heart	165 ± 6	4 of 4	1.12	None
Fat body	411 ± 57	4 of 4	2.78	Up
Ovary	120 ± 5	4 of 4	0.80	Down
Testis	32 ± 3	4 of 4	0.20	Down
Male accessory glands	4 ± 1	0 of 4	0.00	Down
Virgin spermatheca	221 ± 18	4 of 4	1.50	Up
Mated spermatheca	249 ± 16	4 of 4	1.69	Up
Adult carcass	262 ± 14	4 of 4	1.80	Up
Larval CNS	6 ± 0	3 of 4	0.04	Down
Larval Salivary gland	83 ± 19	4 of 4	0.57	Down
Larval midgut	614 ± 25	4 of 4	4.15	Up
Larval tubule	241 ± 6	4 of 4	1.60	Up
Larval hindgut	62 ± 5	4 of 4	0.43	Down
Larval fat body	248 ± 39	4 of 4	1.70	None
Larval trachea	73 ± 3	4 of 4	0.50	Down
Larval carcass	7 ± 1	2 of 4	0.05	Down
S2 cells (growing)	156 ± 12	4 of 4	1.06	None
Whole fly	147 ± 4	4 of 4

Looking for CG1031-RA. 1 entries matched from 18771, in 0 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720