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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG10359-RA through 18771 annotations produced 1 hits

Fibronogen-like (CG10359):

Annotation Number : CG10359
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035452
Gbrowse : chr3L:3612193-3615245 (+) // 100.0 //
Probeset : 1629857_at
Accessions : protein= NP_001137881; /// NP_001137882;, nucleotide= NM_001144409; /// NM_001144410;
Interpro : 0005102 // receptor binding // inferred from electronic annotation
FlyMine data for FBgn0035452.
BDGP gene expression has embryonic in situ data for CG10359: 26 pix of staining in 8 body parts.
Homophila reports that CG10359 is a close match (5e-16) to human gene FGB (NP_005132), a gene associated with Afibrinogenemia, congenital, 202400 (3);Dysfibrinogenemia, beta type (3);Thrombophilia, dysfibrinogenemic (3).
VDRC has 2 RNAi stocks for FBgn0035452 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain12 13 of 4 0.80None
Head41 14 of 4 2.60Up
Eye10 24 of 4 0.68None
Thoracicoabdominal ganglion30 34 of 4 1.90Up
Salivary gland41 44 of 4 2.56Up
Crop53 24 of 4 3.40Up
Midgut73 24 of 4 4.60Up
Tubule9 00 of 4 0.60Down
Hindgut63 24 of 4 4.00Up
Heart134 34 of 4 8.36Up
Fat body9 20 of 4 0.59Down
Ovary1 00 of 4 0.10Down
Testis8 00 of 4 0.50Down
Male accessory glands12 11 of 4 0.80None
Virgin spermatheca6 00 of 4 0.38Down
Mated spermatheca10 12 of 4 0.65None
Adult carcass56 34 of 4 3.50Up
Larval CNS119 184 of 4 7.43Up
Larval Salivary gland49 34 of 4 3.09Up
Larval midgut158 94 of 4 9.87Up
Larval tubule90 64 of 4 5.60Up
Larval hindgut430 274 of 426.80Up
Larval fat body11 20 of 4 0.70None
Larval trachea102 104 of 4 6.37Up
Larval carcass614 434 of 438.28Up
S2 cells (growing)155 124 of 4 9.71Up
Whole fly16 13 of 4

Looking for CG10359-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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