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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG10399-RA through 18771 annotations produced 1 hits



(CG10399):

Annotation Number : CG10399
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0031877
Gbrowse : chr2L:6960442-6961473 (+) // 100.0 //
Probeset : 1633760_at
Accessions : protein= NP_609089;, nucleotide= NM_135245;
Pathway : 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005875 // microtubule associated
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004419 // hydroxymethylglutaryl-CoA lyase acti
FlyMine data for FBgn0031877.
Homophila reports that CG10399 is a close match (1e-99) to human gene HMGCL (NP_000182), a gene associated with HMG-CoA lyase deficiency (3).
VDRC has 3 RNAi stocks for FBgn0031877 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain17 ± 14 of 4 0.20Down
Head69 ± 74 of 4 0.90None
Eye48 ± 44 of 4 0.63Down
Thoracicoabdominal ganglion21 ± 24 of 4 0.30Down
Salivary gland64 ± 54 of 4 0.85None
Crop33 ± 24 of 4 0.40Down
Midgut82 ± 24 of 4 1.10None
Tubule325 ± 294 of 4 4.30Up
Hindgut76 ± 34 of 4 1.00None
Heart121 ± 44 of 4 1.60Up
Fat body150 ± 294 of 4 1.99Up
Ovary70 ± 44 of 4 0.90None
Testis10 ± 04 of 4 0.10Down
Male accessory glands28 ± 34 of 4 0.40Down
Virgin spermatheca137 ± 54 of 4 1.81Up
Mated spermatheca102 ± 64 of 4 1.35Up
Adult carcass89 ± 54 of 4 1.20None
Larval CNS36 ± 44 of 4 0.49Down
Larval Salivary gland178 ± 104 of 4 2.35Up
Larval midgut70 ± 24 of 4 0.93None
Larval tubule55 ± 14 of 4 0.70Down
Larval hindgut120 ± 64 of 4 1.58Up
Larval fat body59 ± 74 of 4 0.80None
Larval trachea97 ± 154 of 4 1.29None
Larval carcass90 ± 94 of 4 1.20None
S2 cells (growing)43 ± 14 of 4 0.57Down
Whole fly76 ± 14 of 4

Looking for CG10399-RA. 1 entries matched from 18771, in 0 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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