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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG10975-RA through 18771 annotations produced 1 hits

Protein tyrosine phosphatase 69D (Ptp69D):

Annotation Number : CG10975
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0014007
Gbrowse : chr3L:12728048-12734668 (+) // 100.0 //
Probeset : 1623602_a_at
Accessions : protein= NP_524048; /// NP_788502;, nucleotide= NM_079324; /// NM_176324;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine ph
FlyMine data for FBgn0014007.
BDGP gene expression has embryonic in situ data for Ptp69D: 9 pix of staining in 6 body parts.
Homophila reports that CG10975 is a close match (7e-38) to human gene PTP1B;PTPN1 (NP_002818), a gene associated with [Abdominal body fat distribution, modifier of], 609830 (3);{Insulin resistance, susceptibility to} (3).
BioGrid reports that CG10975 interacts with CG10443 CG10443 CG8355 CG1817 CG1817 CG17943 CG18243 CG11516 CG11516 .
TRiP has 2 RNAi stocks for FBgn0014007 available for purchase.
VDRC has 8 RNAi stocks for FBgn0014007 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain36 44 of 4 0.80None
Head26 34 of 4 0.50Down
Eye20 14 of 4 0.44Down
Thoracicoabdominal ganglion39 24 of 4 0.80None
Salivary gland27 43 of 4 0.59Down
Crop34 14 of 4 0.70Down
Midgut21 14 of 4 0.40Down
Tubule26 14 of 4 0.60Down
Hindgut24 34 of 4 0.50Down
Heart30 54 of 4 0.64Down
Fat body35 64 of 4 0.75Down
Ovary201 94 of 4 4.20Up
Testis23 04 of 4 0.50Down
Male accessory glands33 24 of 4 0.70Down
Virgin spermatheca50 74 of 4 1.07None
Mated spermatheca51 34 of 4 1.09None
Adult carcass26 54 of 4 0.50Down
Larval CNS252 214 of 4 5.31Up
Larval Salivary gland61 14 of 4 1.29Up
Larval midgut34 04 of 4 0.72Down
Larval tubule84 44 of 4 1.80Up
Larval hindgut49 34 of 4 1.04None
Larval fat body47 44 of 4 1.00None
Larval trachea31 74 of 4 0.65Down
Larval carcass46 14 of 4 0.98None
S2 cells (growing)76 54 of 4 1.61Up
Whole fly47 34 of 4

Looking for CG10975-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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