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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG11151-RA through 18771 annotations produced 1 hits

transcript 2 (CG11151):

Annotation Number : CG11151
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0030519
Gbrowse : chrX:13633776-13635138 (+) // 100.0 //
Probeset : 1634720_at
Accessions : protein= NP_572917;, nucleotide= NM_132689;
Pathway : 0005811 // lipid particle // inferred from direct assay
Interpro : 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from sequence or structural similarity /// 0004303 // es
FlyMine data for FBgn0030519.
BDGP gene expression has embryonic in situ data for CG11151: 14 pix of staining in 14 body parts.
Homophila reports that CG11151 is a close match (1e-12) to human gene SCP2 (NP_001007101), a gene associated with Leukoencephalopathy with dystonia and motor neuropathy (3).
BioGrid reports that CG11151 interacts with CG14815 .
VDRC has 3 RNAi stocks for FBgn0030519 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain673 164 of 4 0.60Down
Head1104 1124 of 4 1.00None
Eye1142 624 of 4 1.08None
Thoracicoabdominal ganglion559 184 of 4 0.50Down
Salivary gland748 264 of 4 0.71None
Crop3060 974 of 4 2.90Up
Midgut3696 714 of 4 3.50Up
Tubule1281 934 of 4 1.20Up
Hindgut2527 374 of 4 2.40Up
Heart3309 1674 of 4 3.13Up
Fat body2422 2124 of 4 2.29Up
Ovary506 64 of 4 0.50Down
Testis155 14 of 4 0.10Down
Male accessory glands1038 294 of 4 1.00None
Virgin spermatheca833 384 of 4 0.79None
Mated spermatheca938 504 of 4 0.89None
Adult carcass2077 694 of 4 2.00Up
Larval CNS597 774 of 4 0.57Down
Larval Salivary gland611 244 of 4 0.58Down
Larval midgut3689 1394 of 4 3.49Up
Larval tubule1282 514 of 4 1.20None
Larval hindgut999 464 of 4 0.95None
Larval fat body5121 5134 of 4 4.80Up
Larval trachea1714 1764 of 4 1.62Up
Larval carcass884 274 of 4 0.84None
S2 cells (growing)1042 214 of 4 0.99None
Whole fly1056 1144 of 4

Looking for CG11151-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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