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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG11261-RA through 18771 annotations produced 1 hits


Annotation Number : CG11261
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0036332
Gbrowse : chr3L:13002498-13004781 (-) // 100.0 //
Probeset : 1635200_at
Accessions : protein= NP_648620;, nucleotide= NM_140363;
Pathway : 0000152 // nuclear ubiquitin ligase complex // inferred from sequence or structural similarity /// 0031461 // cullin-RIN
Interpro : 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation
FlyMine data for FBgn0036332.
BDGP gene expression has embryonic in situ data for CG11261: 4 pix of staining in 1 body parts.
Homophila reports that CG11261 is a close match (4e-18) to human gene CUL4B;MRXHF2;MRXSC;SFM2 (NP_003579), a gene associated with Mental retardation syndrome, X-linked, Cabezas type, 300354 (3);Mental retardation-hypotonic facies syndrome, X-linked, 2, 300639 (3).
VDRC has 3 RNAi stocks for FBgn0036332 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain10 12 of 4 0.20Down
Head22 24 of 4 0.50Down
Eye19 14 of 4 0.42Down
Thoracicoabdominal ganglion8 00 of 4 0.20Down
Salivary gland23 22 of 4 0.51Down
Crop17 24 of 4 0.40Down
Midgut93 44 of 4 2.10Up
Tubule13 03 of 4 0.30Down
Hindgut40 24 of 4 0.90None
Heart45 24 of 4 1.00None
Fat body51 74 of 4 1.13None
Ovary92 34 of 4 2.00Up
Testis74 24 of 4 1.60Up
Male accessory glands12 21 of 4 0.30Down
Virgin spermatheca36 24 of 4 0.81None
Mated spermatheca32 24 of 4 0.71None
Adult carcass34 24 of 4 0.80None
Larval CNS21 44 of 4 0.47Down
Larval Salivary gland19 04 of 4 0.44Down
Larval midgut55 34 of 4 1.23None
Larval tubule23 24 of 4 0.50Down
Larval hindgut37 24 of 4 0.83None
Larval fat body54 64 of 4 1.20None
Larval trachea32 94 of 4 0.72None
Larval carcass20 04 of 4 0.45Down
S2 cells (growing)141 24 of 4 3.13Up
Whole fly45 44 of 4

Looking for CG11261-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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