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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG11348-RB through 18771 annotations produced 1 hits

AChR protein of Drosophila (nAcRbeta-64B):

Annotation Number : CG11348
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000038
Gbrowse : chr3L:4429377-4430229 (+) // 100.0 //
Probeset : 1627219_at
Accessions : protein= NP_523927; /// NP_728994;, nucleotide= NM_079203; /// NM_168086;
Pathway : 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // non-trac
Interpro : 0004872 // receptor activity // inferred from electronic annotation /// 0004889 // nicotinic acetylcholine-activated cat
FlyMine data for FBgn0000038.
BDGP gene expression has embryonic in situ data for nAcRbeta-64B: 4 pix of staining in 1 body parts.
Homophila reports that CG11348 is a close match (1e-11) to human gene GLRB (NP_000815), a gene associated with Hyperekplexia, autosomal recessive, 149400 (3).
TRiP has 1 RNAi stocks for FBgn0000038 available for purchase.
VDRC has 6 RNAi stocks for FBgn0000038 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain252 114 of 443.40Up
Head13 23 of 4 2.40Up
Eye36 44 of 4 6.27Up
Thoracicoabdominal ganglion275 144 of 447.30Up
Salivary gland15 31 of 4 2.57None
Crop10 01 of 4 1.70None
Midgut2 00 of 4 0.50None
Tubule8 11 of 4 1.50Up
Hindgut7 21 of 4 1.20None
Heart2 00 of 4 0.39None
Fat body27 163 of 4 4.66None
Ovary3 10 of 4 0.50None
Testis2 00 of 4 0.40None
Male accessory glands11 20 of 4 1.90None
Virgin spermatheca50 54 of 4 8.72Up
Mated spermatheca63 233 of 410.81None
Adult carcass6 00 of 4 1.10None
Larval CNS50 54 of 4 8.70Up
Larval Salivary gland8 12 of 4 1.53None
Larval midgut6 10 of 4 1.04None
Larval tubule8 21 of 4 1.50None
Larval hindgut7 11 of 4 1.24None
Larval fat body6 10 of 4 1.00None
Larval trachea3 20 of 4 0.61None
Larval carcass4 10 of 4 0.79None
S2 cells (growing)5 00 of 4 0.89None
Whole fly5 20 of 4

Looking for CG11348-RB. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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