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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG11621-RB through 18771 annotations produced 1 hits



dPI 3-kinase (Pi3K68D):

Annotation Number : CG11621
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0015278
Gbrowse : chr3L:11779143-11783108 (-) // 100.0 //
Probeset : 1625233_at
Accessions : protein= NP_001163420; /// NP_524028; /// NP_729743; /// NP_729745;, nucleotide= NM_001169949; /// NM_079304; /// NM_168475; /// NM_168476;
Pathway : engulfment // inferred from mutant phenotype /// 0006974 // response to DNA damage stimulus // inferred from mutant phe
Interpro : 0005942 // phosphoinositide 3-kinase complex // inferred from electronic annotation
FlyMine data for FBgn0015278.
BDGP gene expression has embryonic in situ data for Pi3K68D: 6 pix of staining in 1 body parts.
Homophila reports that CG11621 is a close match (3e-86) to human gene PIK3CA (NP_006209), a gene associated with Breast cancer, somatic, 114480 (3);Colorectal cancer, somatic, 114500 (3);Gastric cancer, somatic, 137215 (3);Hepatocellular carcinoma, somatic, 114550 (3);Keratosis, seborrheic, somatic, 182000 (3);Nevus, epidermal, 162900 (3);Nonsmall cell lung cancer, somatic, 211980 (3);Ovarian cancer, somatic, 604370 (3).
TRiP has 3 RNAi stocks for FBgn0015278 available for purchase.
VDRC has 3 RNAi stocks for FBgn0015278 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain93 ± 64 of 4 1.00None
Head106 ± 84 of 4 1.20None
Eye272 ± 134 of 4 3.06Up
Thoracicoabdominal ganglion66 ± 14 of 4 0.70None
Salivary gland49 ± 34 of 4 0.56Down
Crop65 ± 14 of 4 0.70None
Midgut198 ± 114 of 4 2.20Up
Tubule327 ± 354 of 4 3.70Up
Hindgut115 ± 54 of 4 1.30None
Heart62 ± 24 of 4 0.70None
Fat body45 ± 44 of 4 0.51Down
Ovary160 ± 34 of 4 1.80Up
Testis18 ± 14 of 4 0.20Down
Male accessory glands56 ± 54 of 4 0.60Down
Virgin spermatheca58 ± 24 of 4 0.65Down
Mated spermatheca54 ± 34 of 4 0.61Down
Adult carcass65 ± 44 of 4 0.70None
Larval CNS70 ± 44 of 4 0.79None
Larval Salivary gland26 ± 64 of 4 0.30Down
Larval midgut316 ± 254 of 4 3.55Up
Larval tubule640 ± 244 of 4 7.20Up
Larval hindgut131 ± 84 of 4 1.47Up
Larval fat body19 ± 34 of 4 0.20Down
Larval trachea103 ± 224 of 4 1.16None
Larval carcass43 ± 24 of 4 0.49Down
S2 cells (growing)62 ± 14 of 4 0.70None
Whole fly89 ± 94 of 4

Looking for CG11621-RB. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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