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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG11678-RA through 18771 annotations produced 1 hits

actin-related protein (Actr13E):

Annotation Number : CG11678
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011741
Gbrowse : chrX:15629805-15631109 (-) // 100.0 //
Probeset : 1639228_at
Accessions : protein= NP_511165;, nucleotide= NM_078610;
Pathway : 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotatio
Interpro : 0005200 // structural constituent of cytoskeleton // inferred from sequence or structural similarity /// 0005515 // prot
FlyMine data for FBgn0011741.
BDGP gene expression has embryonic in situ data for Actr13E: 4 pix of staining in 1 body parts.
Homophila reports that CG11678 is a close match (8e-41) to human gene ACTA2;ACTSA;AAT6 (NP_001604), a gene associated with Aortic aneurysm, familial thoracic 6, 611788 (3).
BioGrid reports that CG11678 interacts with CG4362 CG12548 CG12819 CG13363 CG13917 CG14716 CG1489 CG2168 CG3365 CG3645 CG4916 CG4993 CG5089 CG5613 CG6105 CG6410 CG7348 CG8366 CG9258 CG33517 .
VDRC has 2 RNAi stocks for FBgn0011741 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain155 24 of 4 1.10None
Head136 44 of 4 0.90None
Eye165 44 of 4 1.14Up
Thoracicoabdominal ganglion157 64 of 4 1.10None
Salivary gland152 134 of 4 1.05None
Crop187 34 of 4 1.30Up
Midgut127 44 of 4 0.90Down
Tubule258 64 of 4 1.80Up
Hindgut192 64 of 4 1.30Up
Heart158 44 of 4 1.09None
Fat body154 194 of 4 1.06None
Ovary200 24 of 4 1.40Up
Testis27 04 of 4 0.20Down
Male accessory glands166 64 of 4 1.10Up
Virgin spermatheca99 24 of 4 0.68Down
Mated spermatheca102 54 of 4 0.70Down
Adult carcass159 174 of 4 1.10None
Larval CNS354 104 of 4 2.44Up
Larval Salivary gland312 34 of 4 2.15Up
Larval midgut107 34 of 4 0.74Down
Larval tubule247 34 of 4 1.70Up
Larval hindgut199 34 of 4 1.37Up
Larval fat body171 194 of 4 1.20None
Larval trachea261 24 of 4 1.80Up
Larval carcass271 174 of 4 1.87Up
S2 cells (growing)385 84 of 4 2.66Up
Whole fly145 54 of 4

Looking for CG11678-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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