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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG12010-RA through 18771 annotations produced 1 hits



(CG12010):

Annotation Number : CG12010
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035443
Gbrowse : chr3L:3374307-3376649 (+) // 100.0 //
Probeset : 1633799_a_at
Accessions : protein= NP_647812; /// NP_728878;, nucleotide= NM_139555; /// NM_168030;
Pathway : 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity
Interpro : "0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from ph
FlyMine data for FBgn0035443.
Homophila reports that CG12010 is a close match (4e-17) to human gene CAR;CMAR;PGN;SPG7 (NP_955399), a gene associated with Spastic paraplegia-7, 607259 (3).
BioGrid reports that CG12010 interacts with CG5569 CG1474 CG16728 CG17265 CG1999 CG3081 CG6416 CG7238 CG7257 CG7856 CG8831 CG17450 CG32819 CG32820 .
VDRC has 2 RNAi stocks for FBgn0035443 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain15 ± 14 of 4 0.30Down
Head15 ± 14 of 4 0.30Down
Eye16 ± 14 of 4 0.38Down
Thoracicoabdominal ganglion24 ± 24 of 4 0.60Down
Salivary gland39 ± 94 of 4 0.92None
Crop27 ± 23 of 4 0.60Down
Midgut27 ± 23 of 4 0.60Down
Tubule31 ± 24 of 4 0.70Down
Hindgut17 ± 24 of 4 0.40Down
Heart24 ± 14 of 4 0.55Down
Fat body38 ± 34 of 4 0.89None
Ovary78 ± 24 of 4 1.80Up
Testis7 ± 10 of 4 0.20Down
Male accessory glands33 ± 34 of 4 0.80Down
Virgin spermatheca24 ± 24 of 4 0.56Down
Mated spermatheca24 ± 14 of 4 0.55Down
Adult carcass26 ± 02 of 4 0.60Down
Larval CNS33 ± 44 of 4 0.78Down
Larval Salivary gland26 ± 22 of 4 0.61Down
Larval midgut20 ± 41 of 4 0.47Down
Larval tubule37 ± 14 of 4 0.90Down
Larval hindgut25 ± 24 of 4 0.59Down
Larval fat body17 ± 31 of 4 0.40Down
Larval trachea37 ± 44 of 4 0.86None
Larval carcass21 ± 23 of 4 0.49Down
S2 cells (growing)54 ± 24 of 4 1.26Up
Whole fly43 ± 14 of 4

Looking for CG12010-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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