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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG12287-RB through 18771 annotations produced 1 hits

POU domain protein 2 (pdm2):

Annotation Number : CG12287
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004394
Gbrowse : chr2L:12657828-12686306 (+) // 99.81 //
Probeset : 1624491_a_at
Accessions : protein= NP_523558; /// NP_723763;, nucleotide= NM_078834; /// NM_165017;
Pathway : DNA-dependent // inferred from sequence or structural similarity /// 0006355 // regulation of transcription
Interpro : DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription
FlyMine data for FBgn0004394.
BDGP gene expression has embryonic in situ data for pdm2: 55 pix of staining in 31 body parts.
Homophila reports that CG12287 is a close match (4e-16) to human gene POU6F2;WT5;WTSL (NP_009183), a gene associated with {Wilms tumor susceptibility-5}, 601583 (3).
TRiP has 1 RNAi stocks for FBgn0004394 available for purchase.
VDRC has 3 RNAi stocks for FBgn0004394 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain32 24 of 4 2.20Up
Head10 14 of 4 0.70None
Eye2 10 of 4 0.20Down
Thoracicoabdominal ganglion63 34 of 4 4.40Up
Salivary gland10 40 of 4 0.70None
Crop12 14 of 4 0.80None
Midgut75 84 of 4 5.20Up
Tubule6 00 of 4 0.40Down
Hindgut35 34 of 4 2.50Up
Heart1 00 of 4 0.12Down
Fat body7 11 of 4 0.49Down
Ovary2 10 of 4 0.20Down
Testis4 01 of 4 0.30Down
Male accessory glands10 11 of 4 0.70None
Virgin spermatheca5 10 of 4 0.38Down
Mated spermatheca7 11 of 4 0.49Down
Adult carcass6 10 of 4 0.40Down
Larval CNS17 24 of 4 1.22None
Larval Salivary gland5 10 of 4 0.36Down
Larval midgut64 54 of 4 4.41Up
Larval tubule6 21 of 4 0.40Down
Larval hindgut34 54 of 4 2.34Up
Larval fat body4 00 of 4 0.30Down
Larval trachea1 30 of 4 0.14Down
Larval carcass8 02 of 4 0.60Down
S2 cells (growing)3 00 of 4 0.27Down
Whole fly14 14 of 4

Looking for CG12287-RB. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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