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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG1236-RA through 18771 annotations produced 1 hits

/// (CG1236 /// DsimCG1236):

Annotation Number : CG1236
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0037370
Gbrowse : chr3R:1562465-1563996 (+) // 100.0 //
Probeset : 1631755_at
Accessions : protein= NP_649579;, nucleotide= NM_141322;
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004617 // phosphoglycerate dehydrogenase acti
FlyMine data for FBgn0037370.
BDGP gene expression has embryonic in situ data for CG1236: 15 pix of staining in 6 body parts.
Homophila reports that CG1236 is a close match (1e-20) to human gene PHGDH (NP_006614), a gene associated with Phosphoglycerate dehydrogenase deficiency, 601815 (3).
VDRC has 3 RNAi stocks for FBgn0037370 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain42 14 of 4 0.40Down
Head59 54 of 4 0.60Down
Eye59 44 of 4 0.60Down
Thoracicoabdominal ganglion51 34 of 4 0.50Down
Salivary gland149 34 of 4 1.49Up
Crop152 84 of 4 1.50Up
Midgut41 24 of 4 0.40Down
Tubule116 34 of 4 1.20Up
Hindgut74 24 of 4 0.70Down
Heart74 34 of 4 0.74Down
Fat body82 44 of 4 0.82Down
Ovary200 24 of 4 2.00Up
Testis50 44 of 4 0.50Down
Male accessory glands186 64 of 4 1.90Up
Virgin spermatheca143 64 of 4 1.42Up
Mated spermatheca146 64 of 4 1.46Up
Adult carcass80 94 of 4 0.80None
Larval CNS91 44 of 4 0.91None
Larval Salivary gland287 204 of 4 2.86Up
Larval midgut41 44 of 4 0.41Down
Larval tubule120 54 of 4 1.20Up
Larval hindgut131 44 of 4 1.31Up
Larval fat body2262 2254 of 422.50Up
Larval trachea129 194 of 4 1.29Up
Larval carcass100 54 of 4 1.00None
S2 cells (growing)85 14 of 4 0.85Down
Whole fly100 44 of 4

Looking for CG1236-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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