FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG14723-RA through 18771 annotations produced 1 hits

Histamine-gated chloride channel subunit 1 (HisCl1):

Annotation Number : CG14723
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0037950
Gbrowse : chr3R:7613151-7615079 (+) // 100.0 //
Probeset : 1626897_at
Accessions : protein= NP_001163591; /// NP_650116; /// NP_731632; /// NP_996196;, nucleotide= NM_001170120; /// NM_141859; /// NM_169429; /// NM_206474;
Pathway : 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic an
Interpro : 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion cha
FlyMine data for FBgn0037950.
Homophila reports that CG14723 is a close match (2e-17) to human gene CAE2;ECA2;GABRG2;GEFSP3 (NP_000807), a gene associated with Epilepsy, childhood absence, 2, 607681 (3);Epilepsy, generalized, with febrile seizures plus, type 3, 604233 (3);Febrile convulsions, familial, 8, 611277 (3);Myoclonic epilepsy, severe, of infancy, 607208 (3).
TRiP has 1 RNAi stocks for FBgn0037950 available for purchase.
VDRC has 2 RNAi stocks for FBgn0037950 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	30 ± 2	4 of 4	5.30	Up
Head	62 ± 6	4 of 4	10.90	Up
Eye	217 ± 4	4 of 4	37.90	Up
Thoracicoabdominal ganglion	35 ± 2	4 of 4	6.20	Up
Salivary gland	10 ± 4	0 of 4	1.74	None
Crop	4 ± 1	0 of 4	0.90	None
Midgut	4 ± 1	0 of 4	0.70	None
Tubule	6 ± 1	0 of 4	1.10	None
Hindgut	7 ± 2	0 of 4	1.30	None
Heart	5 ± 1	0 of 4	0.95	None
Fat body	4 ± 2	0 of 4	0.73	None
Ovary	3 ± 1	0 of 4	0.60	None
Testis	10 ± 1	2 of 4	1.70	None
Male accessory glands	67 ± 3	4 of 4	11.80	Up
Virgin spermatheca	3 ± 0	0 of 4	0.69	None
Mated spermatheca	3 ± 1	0 of 4	0.62	None
Adult carcass	3 ± 0	0 of 4	0.60	None
Larval CNS	9 ± 2	1 of 4	1.69	None
Larval Salivary gland	5 ± 0	0 of 4	0.97	None
Larval midgut	6 ± 3	0 of 4	1.14	None
Larval tubule	4 ± 0	0 of 4	0.80	None
Larval hindgut	4 ± 2	0 of 4	0.74	None
Larval fat body	12 ± 2	1 of 4	2.10	None
Larval trachea	4 ± 4	0 of 4	0.71	None
Larval carcass	5 ± 1	0 of 4	0.90	None
S2 cells (growing)	5 ± 1	0 of 4	0.88	None
Whole fly	5 ± 1	0 of 4

Looking for CG14723-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720