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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG1644-RA through 18771 annotations produced 1 hits

Cyp6t1 (Cyp6t1):

Annotation Number : CG1644
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0031182
Gbrowse : chrX:21388460-21390196 (-) // 100.0 //
Probeset : 1626689_at
Accessions : protein= NP_608457;, nucleotide= NM_134613;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0031182.
BDGP gene expression has embryonic in situ data for Cyp6t1: 12 pix of staining in 3 body parts.
Homophila reports that CG1644 is a close match (1e-12) to human gene CYP11B2 (NP_000489), a gene associated with Aldosterone to renin ratio raised (3);Hypoaldosteronism, congenital, due to CMO I deficiency, 203400 (3);Hypoaldosteronism, congenital, due to CMO II deficiency, 610600 (3);{Low renin hypertension, susceptibility to} (3).
BioGrid reports that CG1644 interacts with CG7765 .
VDRC has 3 RNAi stocks for FBgn0031182 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain40 34 of 4 0.50Down
Head129 134 of 4 1.80Up
Eye45 74 of 4 0.61Down
Thoracicoabdominal ganglion64 24 of 4 0.90None
Salivary gland14 20 of 4 0.20Down
Crop6 00 of 4 0.10Down
Midgut283 164 of 4 3.90Up
Tubule80 44 of 4 1.10None
Hindgut26 44 of 4 0.40Down
Heart88 74 of 4 1.21None
Fat body192 184 of 4 2.62Up
Ovary61 24 of 4 0.80None
Testis5 01 of 4 0.10Down
Male accessory glands6 11 of 4 0.10Down
Virgin spermatheca135 84 of 4 1.85Up
Mated spermatheca140 214 of 4 1.91None
Adult carcass177 94 of 4 2.40Up
Larval CNS1 00 of 4 0.02Down
Larval Salivary gland5 20 of 4 0.08Down
Larval midgut255 414 of 4 3.48Up
Larval tubule32 34 of 4 0.40Down
Larval hindgut7 01 of 4 0.09Down
Larval fat body330 374 of 4 4.50Up
Larval trachea1 10 of 4 0.02Down
Larval carcass5 10 of 4 0.07Down
S2 cells (growing)23 14 of 4 0.32Down
Whole fly73 54 of 4

Looking for CG1644-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

measure downtime