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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG16738-RA through 18771 annotations produced 1 hits

(March 2006 (FlyBase/BDGP 5.3)):

Annotation Number : CG16738
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : slp1
Gbrowse :
Probeset : 1640129_at
Accessions : protein= P32030 /// Q961V5, nucleotide=
FlyMine data for slp1.
Homophila reports that CG16738 is a close match (4e-12) to human gene AIID;FOXP3;IPEX;PIDX;XPID (NP_054728), a gene associated with Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked, 304790 (3);{Diabetes mellitus, type I, susceptibility to}, 222100 (3).
BioGrid reports that CG16738 interacts with CG8384 CG3731 CG8597 CG4889 CG4889 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain83 44 of 4 6.30Up
Head58 24 of 4 4.40Up
Eye115 44 of 4 8.71Up
Thoracicoabdominal ganglion112 44 of 4 8.50Up
Salivary gland17 50 of 4 1.31None
Crop6 20 of 4 0.50None
Midgut2 10 of 4 0.20Down
Tubule4 00 of 4 0.30Down
Hindgut6 30 of 4 0.50None
Heart2 00 of 4 0.16Down
Fat body9 80 of 4 0.70None
Ovary0 00 of 4 0.10Down
Testis3 10 of 4 0.30Down
Male accessory glands8 30 of 4 0.70None
Virgin spermatheca13 13 of 4 1.04None
Mated spermatheca15 53 of 4 1.20None
Adult carcass15 11 of 4 1.20None
Larval CNS98 74 of 4 7.45Up
Larval Salivary gland1 00 of 4 0.08Down
Larval midgut4 20 of 4 0.33Down
Larval tubule2 10 of 4 0.20Down
Larval hindgut3 10 of 4 0.27Down
Larval fat body2 10 of 4 0.20Down
Larval trachea5 40 of 4 0.41None
Larval carcass11 21 of 4 0.85None
S2 cells (growing)1 10 of 4 0.12Down
Whole fly13 23 of 4

Looking for CG16738-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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