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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG17148-RA through 18771 annotations produced 1 hits

Esterase P (Est-P):

Annotation Number : CG17148
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000594
Gbrowse : chr3L:12183837-12185528 (+) // 100.0 //
Probeset : 1637674_at
Accessions : protein= NP_788501;, nucleotide= NM_176323;
Pathway : 0005576 // extracellular region // inferred from electronic annotation
Interpro : 0004091 // carboxylesterase activity // inferred from sequence or structural similarity /// 0004091 // carboxylesterase
FlyMine data for FBgn0000594.
Homophila reports that CG17148 is a close match (1e-20) to human gene AITD3;TG (NP_003226), a gene associated with Goiter, adolescent multinodular (1);Goiter, nonendemic, simple (3);Hypothyroidism, hereditary congenital (3);{Autoimmune thyroid disease, susceptibility to 3}, 608175 (3).
VDRC has 2 RNAi stocks for FBgn0000594 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1 00 of 4 0.60None
Head6 13 of 4 1.90None
Eye4 10 of 4 1.34None
Thoracicoabdominal ganglion3 00 of 4 0.90None
Salivary gland42 24 of 413.02Up
Crop5 11 of 4 1.50None
Midgut4 00 of 4 1.30None
Tubule4 10 of 4 1.50None
Hindgut3 00 of 4 1.10None
Heart6 11 of 4 1.88None
Fat body8 32 of 4 2.45Up
Ovary1 00 of 4 0.40None
Testis4 00 of 4 1.20None
Male accessory glands6 10 of 4 2.10None
Virgin spermatheca14 14 of 4 4.40Up
Mated spermatheca8 03 of 4 2.63Up
Adult carcass7 21 of 4 2.30None
Larval CNS2 11 of 4 0.86None
Larval Salivary gland8 11 of 4 2.74Up
Larval midgut1 00 of 4 0.52None
Larval tubule23 14 of 4 7.30Up
Larval hindgut33 54 of 410.22Up
Larval fat body4 10 of 4 1.40None
Larval trachea85 244 of 426.42Up
Larval carcass676 984 of 4208.02Up
S2 cells (growing)2 00 of 4 0.63None
Whole fly3 10 of 4

Looking for CG17148-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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