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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG17759-RA through 18771 annotations produced 1 hits



G-protein-alpha[[q]] (Galpha49B):

Annotation Number : CG17759
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004435
Gbrowse : chr2R:8500245-8507806 (+) // 100.0 //
Probeset : 1624798_s_at
Accessions : protein= NP_523718; /// NP_725191; /// NP_725192; /// NP_725193; /// NP_725194; /// NP_725195; /// NP_725196; /// NP_725197;, nucleotide= NM_078994; /// NM_165919; /// NM_165920; /// NM_165921; /// NM_165922; /// NM_165923; /// NM_165924; /// NM_165925;
Pathway : 0005834 // heterotrimeric G-protein complex // inferred from sequence or structural similarity /// 0005834 // heterotrim
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from mut
FlyMine data for FBgn0004435.
BDGP gene expression has embryonic in situ data for Galpha49B: 8 pix of staining in 16 body parts.
Homophila reports that CG17759 is a close match (5e-71) to human gene AHO;GNAS;GNAS1;GPSA;PHP1A;PHP1B;POH (NP_001070956), a gene associated with Acromegaly, 102200 (3);McCune-Albright syndrome, 174800 (3);Osseous heteroplasia, progressive, 166350 (3);Pituitary ACTH secreting adenoma (3);Prolonged bleeding time, brachydac;Pseudohypoparathyroidism, type Ia, 103580 (3);Pseudohypoparathyroidism, type Ib, 603233 (3);Somatotrophinoma (3).
BioGrid reports that CG17759 interacts with CG5962 CG5962 CG10966 CG6571 CG6571 CG3620 CG7875 CG6518 CG3504 .
TRiP has 4 RNAi stocks for FBgn0004435 available for purchase.
VDRC has 4 RNAi stocks for FBgn0004435 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain158 ± 84 of 4 3.00Up
Head69 ± 104 of 4 1.30None
Eye60 ± 54 of 4 1.16None
Thoracicoabdominal ganglion98 ± 44 of 4 1.90Up
Salivary gland122 ± 174 of 4 2.34Up
Crop209 ± 54 of 4 4.00Up
Midgut118 ± 44 of 4 2.20Up
Tubule69 ± 14 of 4 1.30Up
Hindgut176 ± 114 of 4 3.40Up
Heart95 ± 74 of 4 1.82Up
Fat body122 ± 164 of 4 2.32Up
Ovary31 ± 14 of 4 0.60None
Testis20 ± 34 of 4 0.40Down
Male accessory glands161 ± 134 of 4 3.10Up
Virgin spermatheca60 ± 84 of 4 1.15None
Mated spermatheca77 ± 94 of 4 1.48None
Adult carcass62 ± 54 of 4 1.20None
Larval CNS157 ± 164 of 4 2.99Up
Larval Salivary gland169 ± 54 of 4 3.23Up
Larval midgut122 ± 84 of 4 2.33Up
Larval tubule219 ± 194 of 4 4.20Up
Larval hindgut180 ± 104 of 4 3.43Up
Larval fat body130 ± 144 of 4 2.50Up
Larval trachea64 ± 104 of 4 1.22None
Larval carcass118 ± 124 of 4 2.26Up
S2 cells (growing)216 ± 114 of 4 4.12Up
Whole fly52 ± 84 of 4

Looking for CG17759-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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