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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG17988-RA through 18771 annotations produced 1 hits

Ance-3 (Ance-3):

Annotation Number : CG17988
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032536
Gbrowse : chr2L:13914724-13918249 (+) // 100.0 //
Probeset : 1628955_at
Accessions : protein= NP_001033904;, nucleotide= NM_001038815;
Pathway : 0016020 // membrane // inferred from electronic annotation
Interpro : 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred f
FlyMine data for FBgn0032536.
Homophila reports that CG17988 is a close match (5e-135) to human gene ACE;ACE1;DCP1 (NP_000780), a gene associated with Renal tubular dysgenesis, 267430 (3);[Angiotensin I-converting enzyme, benign serum increase] (3);{Alzheimer disease, susceptibility to}, 104300 (3);{Diabetic nephropathy, susceptibility to}, 603933 (3);{Myocardial infarction, susceptibility to} (3);{SARS, progression of} (3).
BioGrid reports that CG17988 interacts with CG3376 .
VDRC has 5 RNAi stocks for FBgn0032536 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2 00 of 4 0.20Down
Head32 24 of 4 3.30Up
Eye10 23 of 4 1.09None
Thoracicoabdominal ganglion3 10 of 4 0.40Down
Salivary gland9 20 of 4 0.98None
Crop3 00 of 4 0.30Down
Midgut3 10 of 4 0.30Down
Tubule3 00 of 4 0.30Down
Hindgut7 10 of 4 0.80None
Heart3 10 of 4 0.40Down
Fat body5 00 of 4 0.52Down
Ovary3 00 of 4 0.30Down
Testis2 00 of 4 0.30Down
Male accessory glands2 00 of 4 0.20Down
Virgin spermatheca8 23 of 4 0.90None
Mated spermatheca14 23 of 4 1.44None
Adult carcass25 33 of 4 2.50Up
Larval CNS1 10 of 4 0.12Down
Larval Salivary gland3 00 of 4 0.32Down
Larval midgut1 00 of 4 0.17Down
Larval tubule3 00 of 4 0.30Down
Larval hindgut2 00 of 4 0.20Down
Larval fat body7 30 of 4 0.80None
Larval trachea1 00 of 4 0.15Down
Larval carcass4 10 of 4 0.43Down
S2 cells (growing)2 10 of 4 0.29Down
Whole fly9 12 of 4

Looking for CG17988-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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