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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG18104-RA through 18771 annotations produced 1 hits

arginase (arg):

Annotation Number : CG18104
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0023535
Gbrowse : chrX:403450-422070 (+) // 100.0 //
Probeset : 1637548_at
Accessions : protein= NP_524875;, nucleotide= NM_080136;
Pathway : 0005739 // mitochondrion // inferred from sequence or structural similarity
Interpro : "0004053 // arginase activity // inferred from sequence or structural similarity /// 0004053 // arginase activity // inf
FlyMine data for FBgn0023535.
BDGP gene expression has embryonic in situ data for arg: 11 pix of staining in 2 body parts.
Homophila reports that CG18104 is a close match (5e-61) to human gene ARG1 (NP_000036), a gene associated with Argininemia, 207800 (3).
VDRC has 3 RNAi stocks for FBgn0023535 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain16 14 of 4 0.20Down
Head35 64 of 4 0.50Down
Eye21 54 of 4 0.30Down
Thoracicoabdominal ganglion15 14 of 4 0.20Down
Salivary gland12 20 of 4 0.17Down
Crop17 33 of 4 0.20Down
Midgut9 10 of 4 0.10Down
Tubule15 23 of 4 0.20Down
Hindgut44 34 of 4 0.60Down
Heart526 454 of 4 7.23Up
Fat body1085 1314 of 414.92Up
Ovary4 10 of 4 0.10Down
Testis5 02 of 4 0.10Down
Male accessory glands6 20 of 4 0.10Down
Virgin spermatheca1519 304 of 420.88Up
Mated spermatheca1080 504 of 414.85Up
Adult carcass474 294 of 4 6.50Up
Larval CNS16 34 of 4 0.22Down
Larval Salivary gland20 43 of 4 0.29Down
Larval midgut6 20 of 4 0.09Down
Larval tubule7 21 of 4 0.10Down
Larval hindgut20 54 of 4 0.28Down
Larval fat body217 364 of 4 3.00Up
Larval trachea17 104 of 4 0.23Down
Larval carcass15 14 of 4 0.22Down
S2 cells (growing)262 44 of 4 3.60Up
Whole fly72 44 of 4

Looking for CG18104-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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