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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG1897-RA through 18771 annotations produced 1 hits

chr3R:25382108-25391007 (+) // 100.0 // (muscle specific homeobox):

Annotation Number : CG1897
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1641137_at
Accessions : protein= , nucleotide= NP_477324;
Pathway : "0006355 // regulation of transcription
Interpro : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
FlyMine data for full length.
Homophila reports that CG1897 is a close match (2e-11) to human gene AI4;DLX3;TDO (NP_005211), a gene associated with Amelogenesis imperfecta, hypomaturation-hypoplastic type, with taurodontism, 104510 (3);Trichodontoosseous syndrome, 190320 (3).
BioGrid reports that CG1897 interacts with CG9986 CG8376 CG10393 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain44 14 of 4 1.10None
Head123 284 of 4 3.20None
Eye19 34 of 4 0.52None
Thoracicoabdominal ganglion97 24 of 4 2.50Up
Salivary gland4 10 of 4 0.11Down
Crop554 304 of 414.40Up
Midgut1 00 of 4 0.00Down
Tubule3 01 of 4 0.10Down
Hindgut151 84 of 4 3.90Up
Heart80 64 of 4 2.08Up
Fat body326 314 of 4 8.48Up
Ovary0 00 of 4 0.00Down
Testis23 14 of 4 0.60None
Male accessory glands214 94 of 4 5.60Up
Virgin spermatheca385 284 of 410.01Up
Mated spermatheca299 254 of 4 7.76Up
Adult carcass81 104 of 4 2.10Up
Larval CNS166 214 of 4 4.31Up
Larval Salivary gland570 504 of 414.80Up
Larval midgut1 00 of 4 0.04Down
Larval tubule1 00 of 4 0.00Down
Larval hindgut26 34 of 4 0.69None
Larval fat body162 204 of 4 4.20Up
Larval trachea5 33 of 4 0.15Down
Larval carcass58 34 of 4 1.51None
S2 cells (growing)1 00 of 4 0.05Down
Whole fly38 74 of 4

Looking for CG1897-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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