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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG2198-RB through 18771 annotations produced 1 hits

amalgam (Ama):

Annotation Number : CG2198
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000071
Gbrowse : chr3R:2588314-2590983 (+) // 100.0 //
Probeset : 1623950_s_at
Accessions : protein= NP_476579; /// NP_731114; /// NP_788589;, nucleotide= NM_057231; /// NM_169160; /// NM_176412;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0003823 // antigen binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical in
FlyMine data for FBgn0000071.
BDGP gene expression has embryonic in situ data for Ama: 80 pix of staining in 27 body parts.
Homophila reports that CG2198 is a close match (9e-12) to human gene CAML1;HSAS1;L1CAM (NP_076493), a gene associated with Corpus callosum, partial agenesis of, 304100 (3);CRASH syndrome, 303350 (3);Hydrocephalus due to aqueductal stenosis, 307000 (3);Hydrocephalus with congenital idiopathic intestinal pseudoobstruction, 307000 (3);Hydrocephalus with Hirschsprung disease and cleft palate, 142623 (3);MASA syndrome, 303350 (3).
BioGrid reports that CG2198 interacts with CG30106 CG4057 CG5471 CG7109 CG8292 .
TRiP has 1 RNAi stocks for FBgn0000071 available for purchase.
VDRC has 2 RNAi stocks for FBgn0000071 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain13 21 of 4 0.30None
Head6 10 of 4 0.10Down
Eye4 10 of 4 0.09Down
Thoracicoabdominal ganglion55 44 of 4 1.10None
Salivary gland13 30 of 4 0.28None
Crop18 51 of 4 0.40None
Midgut5 10 of 4 0.10Down
Tubule2 00 of 4 0.10Down
Hindgut5 00 of 4 0.10Down
Heart5 10 of 4 0.11Down
Fat body5 10 of 4 0.12Down
Ovary1 00 of 4 0.00Down
Testis8 10 of 4 0.20Down
Male accessory glands6 20 of 4 0.10Down
Virgin spermatheca5 00 of 4 0.10Down
Mated spermatheca6 20 of 4 0.14Down
Adult carcass7 20 of 4 0.20Down
Larval CNS1239 904 of 425.34Up
Larval Salivary gland13 20 of 4 0.27None
Larval midgut170 254 of 4 3.49Up
Larval tubule41 64 of 4 0.80None
Larval hindgut63 84 of 4 1.29None
Larval fat body4432 5514 of 490.60Up
Larval trachea104 304 of 4 2.14Up
Larval carcass253 424 of 4 5.19Up
S2 cells (growing)637 204 of 413.03Up
Whole fly48 124 of 4

Looking for CG2198-RB. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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