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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG3324-RA through 18771 annotations produced 1 hits

cGMP-dependent protein kinase 21D (Pkg21D):

Annotation Number : CG3324
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000442
Gbrowse : chr2L:786152-790795 (-) // 100.0 //
Probeset : 1635406_at
Accessions : protein= NP_477213;, nucleotide= NM_057865;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0000442.
BDGP gene expression has embryonic in situ data for Pkg21D: 15 pix of staining in 3 body parts.
Homophila reports that CG3324 is a close match (7e-11) to human gene PHA2B;PRKWNK4;WNK4 (NP_115763), a gene associated with Pseudohypoaldosteronism type II, 145260 (3).
TRiP has 1 RNAi stocks for FBgn0000442 available for purchase.
VDRC has 3 RNAi stocks for FBgn0000442 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain27 14 of 4 1.70None
Head22 00 of 4 1.40Up
Eye47 34 of 4 2.89Up
Thoracicoabdominal ganglion42 24 of 4 2.60Up
Salivary gland8 40 of 4 0.49None
Crop2 10 of 4 0.20Down
Midgut7 10 of 4 0.40Down
Tubule480 234 of 429.10Up
Hindgut482 144 of 429.20Up
Heart1 00 of 4 0.07Down
Fat body1 00 of 4 0.07Down
Ovary0 00 of 4 0.00Down
Testis1 00 of 4 0.10Down
Male accessory glands1 00 of 4 0.10Down
Virgin spermatheca1 00 of 4 0.10Down
Mated spermatheca2 00 of 4 0.14Down
Adult carcass4 10 of 4 0.30Down
Larval CNS2 10 of 4 0.15Down
Larval Salivary gland1 00 of 4 0.07Down
Larval midgut11 20 of 4 0.72None
Larval tubule329 354 of 419.90Up
Larval hindgut404 54 of 424.51Up
Larval fat body1 00 of 4 0.10Down
Larval trachea0 00 of 4 0.05Down
Larval carcass5 10 of 4 0.31Down
S2 cells (growing)1 00 of 4 0.10Down
Whole fly16 10 of 4

Looking for CG3324-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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