FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG3567-RA through 18771 annotations produced 1 hits

Cyp6u1 (Cyp6u1):

Annotation Number : CG3567
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033121
Gbrowse : chr2R:2859616-2862491 (-) // 100.0 //
Probeset : 1633008_at
Accessions : protein= NP_610252;, nucleotide= NM_136408;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0033121.
Homophila reports that CG3567 is a close match (4e-11) to human gene CYP2A;CYP2A3;CYP2A6;P450C2A (NP_000753), a gene associated with Coumarin resistance, 122700 (3);{Lung cancer, resistance to}, 211980 (3);{Nicotine addiction, protection from}, 188890 (3).
VDRC has 1 RNAi stocks for FBgn0033121 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	141 ± 5	4 of 4	1.10	None
Head	108 ± 3	4 of 4	0.90	None
Eye	91 ± 2	4 of 4	0.74	Down
Thoracicoabdominal ganglion	176 ± 3	4 of 4	1.40	Up
Salivary gland	55 ± 8	4 of 4	0.45	Down
Crop	118 ± 8	4 of 4	1.00	None
Midgut	116 ± 2	4 of 4	0.90	None
Tubule	150 ± 7	4 of 4	1.20	Up
Hindgut	136 ± 4	4 of 4	1.10	None
Heart	110 ± 3	4 of 4	0.90	None
Fat body	117 ± 8	4 of 4	0.96	None
Ovary	259 ± 9	4 of 4	2.10	Up
Testis	88 ± 1	4 of 4	0.70	Down
Male accessory glands	46 ± 2	4 of 4	0.40	Down
Virgin spermatheca	124 ± 2	4 of 4	1.01	None
Mated spermatheca	146 ± 5	4 of 4	1.19	None
Adult carcass	129 ± 9	4 of 4	1.10	None
Larval CNS	108 ± 9	4 of 4	0.88	None
Larval Salivary gland	49 ± 4	4 of 4	0.40	Down
Larval midgut	195 ± 7	4 of 4	1.58	Up
Larval tubule	230 ± 7	4 of 4	1.90	Up
Larval hindgut	115 ± 4	4 of 4	0.94	None
Larval fat body	112 ± 6	4 of 4	0.90	None
Larval trachea	87 ± 6	4 of 4	0.71	Down
Larval carcass	101 ± 4	4 of 4	0.83	None
S2 cells (growing)	118 ± 1	4 of 4	0.96	None
Whole fly	123 ± 8	4 of 4

Looking for CG3567-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720