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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG4027-RA through 18771 annotations produced 1 hits



5C actin (Act5C):

Annotation Number : CG4027
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000042
Gbrowse : chrX:5794896-5798206 (+) // 99.76 //
Probeset : 1626163_s_at
Accessions : protein= NP_001014725; /// NP_001014726; /// NP_511052; /// NP_727048;, nucleotide= NM_001014725; /// NM_001014726; /// NM_078497; /// NM_167053;
Pathway : engulfment // inferred from mutant phenotype /// 0007010 // cytoskeleton organization // inferred from sequence or stru
Interpro : 0005737 // cytoplasm // inferred from electronic annotation /// 0005811 // lipid particle // inferred from direct assay
FlyMine data for FBgn0000042.
BDGP gene expression has embryonic in situ data for Act5C: 5 pix of staining in 9 body parts.
Homophila reports that CG4027 is a close match (0) to human gene ACTC1;CMD1R;CMH11 (NP_005150), a gene associated with Cardiomyopathy, dilated, 1R (3);Cardiomyopathy, familial hypertrophic, 11, 612098 (3).
BioGrid reports that CG4027 interacts with CG5061 CG4057 CG4313 CG4491 CG4584 CG4785 CG5215 CG5422 CG5466 CG6240 CG6707 CG7518 CG8668 CG9572 CG9911 CG9933 CG12051 Dmel CG34354 .
VDRC has 3 RNAi stocks for FBgn0000042 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2410 ± 244 of 4 0.90Down
Head1986 ± 2214 of 4 0.70Down
Eye2342 ± 1814 of 4 0.85None
Thoracicoabdominal ganglion2293 ± 1074 of 4 0.80Down
Salivary gland5980 ± 1044 of 4 2.17Up
Crop2055 ± 644 of 4 0.70Down
Midgut5158 ± 434 of 4 1.90Up
Tubule3871 ± 2834 of 4 1.40Up
Hindgut4217 ± 1234 of 4 1.50Up
Heart2024 ± 614 of 4 0.73Down
Fat body1205 ± 2814 of 4 0.44Down
Ovary2377 ± 314 of 4 0.90Down
Testis1718 ± 564 of 4 0.60Down
Male accessory glands2306 ± 2694 of 4 0.80None
Virgin spermatheca371 ± 524 of 4 0.13Down
Mated spermatheca666 ± 1014 of 4 0.24Down
Adult carcass1612 ± 764 of 4 0.60Down
Larval CNS2751 ± 854 of 4 1.00None
Larval Salivary gland6272 ± 2084 of 4 2.27Up
Larval midgut5596 ± 1614 of 4 2.03Up
Larval tubule4343 ± 884 of 4 1.60Up
Larval hindgut4448 ± 544 of 4 1.61Up
Larval fat body4931 ± 4744 of 4 1.80Up
Larval trachea6010 ± 3534 of 4 2.18Up
Larval carcass3247 ± 874 of 4 1.18Up
S2 cells (growing)4691 ± 944 of 4 1.70Up
Whole fly2759 ± 1154 of 4

Looking for CG4027-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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