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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG4123-RB through 18771 annotations produced 1 hits

Multiple inositol polyphosphate phosphatase 1 (Mipp1):

Annotation Number : CG4123
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0026061
Gbrowse : chr3L:16556726-16566430 (-) // 100.0 //
Probeset : 1626990_s_at
Accessions : protein= NP_524109; /// NP_730177;, nucleotide= NM_079385; /// NM_168672;
Interpro : 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004437 // inositol or phosphatidylinosi
FlyMine data for FBgn0026061.
BDGP gene expression has embryonic in situ data for Mipp1: 20 pix of staining in 10 body parts.
Homophila reports that CG4123 is a close match (2e-24) to human gene MINPP1;HIPER1 (NP_004888), a gene associated with Thyroid carcinoma, follicular, 188470 (3).
VDRC has 3 RNAi stocks for FBgn0026061 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain58 34 of 4 0.20Down
Head251 284 of 4 1.10None
Eye135 114 of 4 0.58Down
Thoracicoabdominal ganglion82 34 of 4 0.40Down
Salivary gland358 114 of 4 1.53Up
Crop1605 444 of 4 6.90Up
Midgut1599 414 of 4 6.80Up
Tubule699 584 of 4 3.00Up
Hindgut1366 644 of 4 5.80Up
Heart153 174 of 4 0.66Down
Fat body82 104 of 4 0.35Down
Ovary66 04 of 4 0.30Down
Testis69 24 of 4 0.30Down
Male accessory glands27 14 of 4 0.10Down
Virgin spermatheca89 74 of 4 0.38Down
Mated spermatheca47 44 of 4 0.20Down
Adult carcass353 214 of 4 1.50Up
Larval CNS12 24 of 4 0.05Down
Larval Salivary gland40 54 of 4 0.17Down
Larval midgut665 254 of 4 2.85Up
Larval tubule29 24 of 4 0.10Down
Larval hindgut266 194 of 4 1.14None
Larval fat body4 11 of 4 0.00Down
Larval trachea223 304 of 4 0.95None
Larval carcass121 104 of 4 0.52Down
S2 cells (growing)1 00 of 4 0.01Down
Whole fly233 124 of 4

Looking for CG4123-RB. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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