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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG4261-RA through 18771 annotations produced 1 hits

89B Helicase (Hel89B):

Annotation Number : CG4261
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0022787
Gbrowse : chr3R:11803001-11809187 (+) // 100.0 //
Probeset : 1627970_at
Accessions : protein= NP_732097;, nucleotide= NM_169693;
Interpro : "0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from elec
FlyMine data for FBgn0022787.
BDGP gene expression has embryonic in situ data for Hel89B: 28 pix of staining in 13 body parts.
Homophila reports that CG4261 is a close match (2e-18) to human gene ATRX;MRXHF1;SFM1;SHS;XH2;XNP (NP_612114), a gene associated with Alpha-thalassemia myelodysplasia syndrome, somatic, 300448 (3);Alpha-thalassemia/mental retardation syndrome, 301040 (3);Mental retardation-hypotonic facies syndrome, X-linked, 309580 (3).
BioGrid reports that CG4261 interacts with CG10388 .
TRiP has 1 RNAi stocks for FBgn0022787 available for purchase.
VDRC has 2 RNAi stocks for FBgn0022787 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain311 94 of 4 3.30Up
Head131 64 of 4 1.40Up
Eye204 54 of 4 2.16Up
Thoracicoabdominal ganglion294 94 of 4 3.10Up
Salivary gland291 154 of 4 3.07Up
Crop156 74 of 4 1.70Up
Midgut92 64 of 4 1.00None
Tubule139 14 of 4 1.50Up
Hindgut99 24 of 4 1.00None
Heart302 314 of 4 3.20Up
Fat body72 124 of 4 0.76Down
Ovary129 34 of 4 1.40Up
Testis147 74 of 4 1.60Up
Male accessory glands288 134 of 4 3.00Up
Virgin spermatheca85 44 of 4 0.90None
Mated spermatheca87 54 of 4 0.93None
Adult carcass103 94 of 4 1.10None
Larval CNS303 134 of 4 3.21Up
Larval Salivary gland323 234 of 4 3.41Up
Larval midgut121 74 of 4 1.28Up
Larval tubule133 94 of 4 1.40Up
Larval hindgut129 34 of 4 1.37Up
Larval fat body193 94 of 4 2.00Up
Larval trachea128 114 of 4 1.36Up
Larval carcass108 64 of 4 1.14None
S2 cells (growing)397 74 of 4 4.19Up
Whole fly94 44 of 4

Looking for CG4261-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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