FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG4466-RA through 18771 annotations produced 1 hits

heat shock protein hsp27 (Hsp27):

Annotation Number : CG4466
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0001226
Gbrowse : chr3L:9377164-9378384 (+) // 100.0 //
Probeset : 1628117_at
Accessions : protein= NP_524000;, nucleotide= NM_079276;
Pathway : 0005875 // microtubule associated complex // inferred from direct assay
Interpro : 0005515 // protein binding // inferred from physical interaction
FlyMine data for FBgn0001226.
BDGP gene expression has embryonic in situ data for Hsp27: 49 pix of staining in 15 body parts.
Homophila reports that CG4466 is a close match (8e-11) to human gene CRYA1;CRYAA (NP_000385), a gene associated with Cataract, autosomal dominant nuclear (3);Cataract, congenital, autosomal recessive (3);Cataract, zonular central nuclear, autosomal dominant (3).
BioGrid reports that CG4466 interacts with CG5546 CG7285 CG8155 CG8440 CG9242 CG9638 CG4354 .
TRiP has 2 RNAi stocks for FBgn0001226 available for purchase.
VDRC has 2 RNAi stocks for FBgn0001226 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	43 ± 2	4 of 4	0.00	Down
Head	33 ± 3	4 of 4	0.00	Down
Eye	36 ± 3	4 of 4	0.03	Down
Thoracicoabdominal ganglion	74 ± 2	4 of 4	0.10	Down
Salivary gland	28 ± 3	3 of 4	0.02	Down
Crop	93 ± 15	4 of 4	0.10	Down
Midgut	39 ± 2	4 of 4	0.00	Down
Tubule	1658 ± 458	4 of 4	1.30	None
Hindgut	15 ± 1	4 of 4	0.00	Down
Heart	58 ± 7	4 of 4	0.04	Down
Fat body	47 ± 4	4 of 4	0.04	Down
Ovary	2121 ± 21	4 of 4	1.60	Up
Testis	1075 ± 15	4 of 4	0.80	None
Male accessory glands	27 ± 5	3 of 4	0.00	Down
Virgin spermatheca	90 ± 9	4 of 4	0.07	Down
Mated spermatheca	396 ± 159	4 of 4	0.30	Down
Adult carcass	58 ± 20	4 of 4	0.00	Down
Larval CNS	2217 ± 203	4 of 4	1.68	Up
Larval Salivary gland	1743 ± 343	4 of 4	1.32	None
Larval midgut	171 ± 60	4 of 4	0.13	Down
Larval tubule	3264 ± 190	4 of 4	2.50	Up
Larval hindgut	424 ± 84	4 of 4	0.32	Down
Larval fat body	3988 ± 409	4 of 4	3.00	Up
Larval trachea	939 ± 197	4 of 4	0.71	Down
Larval carcass	1079 ± 296	4 of 4	0.82	None
S2 cells (growing)	288 ± 18	4 of 4	0.22	Down
Whole fly	1323 ± 97	4 of 4

Looking for CG4466-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720