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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG4804-RA through 18771 annotations produced 1 hits

Serpin 31A (Spn31A):

Annotation Number : CG4804
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032178
Gbrowse : chr2L:10060896-10063837 (+) // 100.0 //
Probeset : 1628964_at
Accessions : protein= NP_609341;, nucleotide= NM_135497;
Interpro : 0004867 // serine-type endopeptidase inhibitor activity // inferred from sequence or structural similarity /// 0004867 /
FlyMine data for FBgn0032178.
Homophila reports that CG4804 is a close match (1e-12) to human gene SERPINA10;ZPI (NP_057270), a gene associated with {Venous thrombosis, susceptibility to} (3).
VDRC has 2 RNAi stocks for FBgn0032178 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain17 14 of 4 0.50Down
Head28 14 of 4 0.90None
Eye8 11 of 4 0.26Down
Thoracicoabdominal ganglion23 14 of 4 0.70None
Salivary gland11 60 of 4 0.35Down
Crop153 64 of 4 4.60Up
Midgut14 30 of 4 0.40Down
Tubule49 43 of 4 1.50Up
Hindgut55 44 of 4 1.70Up
Heart40 34 of 4 1.22None
Fat body16 42 of 4 0.49Down
Ovary5 10 of 4 0.20Down
Testis4 10 of 4 0.10Down
Male accessory glands21 20 of 4 0.60None
Virgin spermatheca9 20 of 4 0.29Down
Mated spermatheca13 10 of 4 0.42Down
Adult carcass93 84 of 4 2.80Up
Larval CNS3 10 of 4 0.12Down
Larval Salivary gland12 10 of 4 0.38Down
Larval midgut10 10 of 4 0.32Down
Larval tubule67 54 of 4 2.00Up
Larval hindgut25 24 of 4 0.78None
Larval fat body15 30 of 4 0.50Down
Larval trachea4 30 of 4 0.15Down
Larval carcass50 34 of 4 1.53Up
S2 cells (growing)154 74 of 4 4.65Up
Whole fly33 54 of 4

Looking for CG4804-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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