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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG4894-RA through 18771 annotations produced 1 hits



calcium channel alpha-1 subunit (Ca-alpha1D):

Annotation Number : CG4894
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0001991
Gbrowse : chr2L:16170656-16190086 (+) // 100.0 //
Probeset : 1640092_a_at
Accessions : protein= NP_525104; /// NP_602305; /// NP_723952; /// NP_723953;, nucleotide= NM_080365; /// NM_134429; /// NM_165146; /// NM_165147;
Pathway : 0005891 // voltage-gated calcium channel complex // inferred from electronic annotation /// 0005891 // voltage-gated cal
Interpro : 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity
FlyMine data for FBgn0001991.
Homophila reports that CG4894 is a close match (1e-48) to human gene CDCD2;CMD1E;HB1;IVF;LQT3;SCN5A;SSS1 (NP_001092875), a gene associated with Brugada syndrome 1, 601144 (3);Cardiomyopathy, dilated, 1E, 601154 (3);Heart block, nonprogressive, 113900 (3);Heart block, progressive, type IA, 113900 (3);Long QT syndrome-3, 603830 (3);Sick sinus syndrome 1, 608567 (3);Ventricular fibrillation, idiopathic, 603829 (3).
BioGrid reports that CG4894 interacts with CG2189 .
TRiP has 2 RNAi stocks for FBgn0001991 available for purchase.
VDRC has 3 RNAi stocks for FBgn0001991 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain428 ± 104 of 414.60Up
Head75 ± 34 of 4 2.50Up
Eye292 ± 174 of 4 9.93Up
Thoracicoabdominal ganglion295 ± 74 of 410.00Up
Salivary gland10 ± 31 of 4 0.36Down
Crop71 ± 34 of 4 2.40Up
Midgut13 ± 20 of 4 0.40Down
Tubule4 ± 00 of 4 0.10Down
Hindgut53 ± 04 of 4 1.80Up
Heart119 ± 74 of 4 4.06Up
Fat body6 ± 40 of 4 0.21Down
Ovary0 ± 00 of 4 0.00Down
Testis22 ± 30 of 4 0.70None
Male accessory glands927 ± 664 of 431.50Up
Virgin spermatheca20 ± 14 of 4 0.70None
Mated spermatheca27 ± 54 of 4 0.94None
Adult carcass74 ± 44 of 4 2.50Up
Larval CNS91 ± 214 of 4 3.10Up
Larval Salivary gland6 ± 20 of 4 0.21Down
Larval midgut4 ± 20 of 4 0.15Down
Larval tubule3 ± 10 of 4 0.10Down
Larval hindgut20 ± 24 of 4 0.71None
Larval fat body5 ± 10 of 4 0.20Down
Larval trachea12 ± 61 of 4 0.43Down
Larval carcass91 ± 144 of 4 3.10Up
S2 cells (growing)1 ± 00 of 4 0.05Down
Whole fly29 ± 34 of 4

Looking for CG4894-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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