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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG4966-RB through 18771 annotations produced 1 hits



Hermansky-Pudlak Syndrome 4 ortholog (HPS4):

Annotation Number : CG4966
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0034261
Gbrowse : chr2R:13571101-13578327 (+) // 100.0 //
Probeset : 1640577_a_at
Accessions : protein= NP_001163179; /// NP_611246; /// NP_725707;, nucleotide= NM_001169708; /// NM_137402; /// NM_166245;
Pathway : 0005765 // lysosomal membrane // inferred from direct assay /// 0031902 // late endosome membrane // inferred from direc
Interpro : 0005549 // odorant binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred
FlyMine data for FBgn0034261.
BDGP gene expression has embryonic in situ data for CG4966: 10 pix of staining in 9 body parts.
Homophila reports that CG4966 is a close match (3e-13) to human gene HPS4 (NP_690054), a gene associated with Hermansky-Pudlak syndrome 4, 203300 (3).
BioGrid reports that CG4966 interacts with CG6707 CG6779 .
VDRC has 3 RNAi stocks for FBgn0034261 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain640 ± 414 of 4 5.00Up
Head283 ± 234 of 4 2.20Up
Eye137 ± 54 of 4 1.08None
Thoracicoabdominal ganglion432 ± 164 of 4 3.40Up
Salivary gland163 ± 104 of 4 1.28None
Crop154 ± 54 of 4 1.20None
Midgut75 ± 24 of 4 0.60Down
Tubule248 ± 74 of 4 2.00Up
Hindgut254 ± 34 of 4 2.00Up
Heart69 ± 34 of 4 0.55Down
Fat body247 ± 24 of 4 1.94Up
Ovary254 ± 44 of 4 2.00Up
Testis37 ± 14 of 4 0.30Down
Male accessory glands194 ± 64 of 4 1.50Up
Virgin spermatheca263 ± 204 of 4 2.06Up
Mated spermatheca232 ± 104 of 4 1.82Up
Adult carcass109 ± 54 of 4 0.90None
Larval CNS204 ± 124 of 4 1.61Up
Larval Salivary gland163 ± 84 of 4 1.28None
Larval midgut104 ± 74 of 4 0.82None
Larval tubule1570 ± 514 of 412.30Up
Larval hindgut197 ± 84 of 4 1.55Up
Larval fat body141 ± 134 of 4 1.10None
Larval trachea45 ± 54 of 4 0.36Down
Larval carcass74 ± 84 of 4 0.59Down
S2 cells (growing)69 ± 24 of 4 0.54Down
Whole fly127 ± 114 of 4

Looking for CG4966-RB. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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