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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG4979-RA through 18771 annotations produced 1 hits

sex-specific enzyme 2 (sxe2):

Annotation Number : CG4979
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0038398
Gbrowse : chr3R:11911226-11912951 (+) // 100.0 //
Probeset : 1623935_at
Accessions : protein= NP_650522;, nucleotide= NM_142265;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0008970 // phospholipase A1 activity // inferre
FlyMine data for FBgn0038398.
BDGP gene expression has embryonic in situ data for CG4979: 2 pix of staining in 1 body parts.
Homophila reports that CG4979 is a close match (9e-14) to human gene HDLCQ12;HL;LIPC;LIPH (NP_000227), a gene associated with Hepatic lipase deficiency (3);[High density lipoprotein cholesterol level QTL 12] (3);{Diabetes mellitus, noninsulin-dependent}, 125853 (3).
VDRC has 2 RNAi stocks for FBgn0038398 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain20 24 of 4 0.30Down
Head1253 674 of 418.60Up
Eye1185 464 of 417.54Up
Thoracicoabdominal ganglion10 23 of 4 0.20Down
Salivary gland18 21 of 4 0.28Down
Crop18 34 of 4 0.30Down
Midgut10 14 of 4 0.10Down
Tubule6 00 of 4 0.10Down
Hindgut84 54 of 4 1.30None
Heart17 14 of 4 0.26Down
Fat body12 34 of 4 0.19Down
Ovary5 10 of 4 0.10Down
Testis12 14 of 4 0.20Down
Male accessory glands11 11 of 4 0.20Down
Virgin spermatheca11 14 of 4 0.17Down
Mated spermatheca8 14 of 4 0.12Down
Adult carcass232 184 of 4 3.40Up
Larval CNS6 14 of 4 0.10Down
Larval Salivary gland10 21 of 4 0.16Down
Larval midgut7 03 of 4 0.11Down
Larval tubule15 14 of 4 0.20Down
Larval hindgut19 34 of 4 0.29Down
Larval fat body10 11 of 4 0.20Down
Larval trachea56 184 of 4 0.83None
Larval carcass34 64 of 4 0.51Down
S2 cells (growing)6 02 of 4 0.10Down
Whole fly67 34 of 4

Looking for CG4979-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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