FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG5037-RA through 18771 annotations produced 1 hits

Protoheme IX farnesyltransferase (CG5037):

Annotation Number : CG5037
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032222
Gbrowse : chr2L:10331462-10333129 (+) // 99.66 //
Probeset : 1634270_at
Accessions : protein= NP_609382;, nucleotide= NM_135538;
Pathway : 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electron
Interpro : 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0008495 // protoheme IX farnesyltransfe
FlyMine data for FBgn0032222.
BDGP gene expression has embryonic in situ data for CG5037: 12 pix of staining in 10 body parts.
Homophila reports that CG5037 is a close match (2e-82) to human gene COX10 (NP_001294), a gene associated with Encephalopathy, progressive mitochondrial, with proximal renal tubulopathy due to cytochrome c oxidase deficiency (3).
TRiP has 2 RNAi stocks for FBgn0032222 available for purchase.
VDRC has 2 RNAi stocks for FBgn0032222 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	566 ± 14	4 of 4	1.50	Up
Head	404 ± 13	4 of 4	1.10	None
Eye	387 ± 2	4 of 4	1.05	None
Thoracicoabdominal ganglion	601 ± 28	4 of 4	1.60	Up
Salivary gland	267 ± 14	4 of 4	0.73	Down
Crop	459 ± 8	4 of 4	1.20	Up
Midgut	284 ± 5	4 of 4	0.80	None
Tubule	620 ± 22	4 of 4	1.70	Up
Hindgut	545 ± 32	4 of 4	1.50	Up
Heart	411 ± 15	4 of 4	1.12	None
Fat body	285 ± 39	4 of 4	0.77	None
Ovary	423 ± 5	4 of 4	1.20	None
Testis	217 ± 10	4 of 4	0.60	Down
Male accessory glands	170 ± 9	4 of 4	0.50	Down
Virgin spermatheca	295 ± 8	4 of 4	0.80	None
Mated spermatheca	325 ± 46	4 of 4	0.88	None
Adult carcass	762 ± 52	4 of 4	2.10	Up
Larval CNS	251 ± 35	4 of 4	0.68	Down
Larval Salivary gland	175 ± 9	4 of 4	0.48	Down
Larval midgut	292 ± 27	4 of 4	0.79	None
Larval tubule	125 ± 11	4 of 4	0.30	Down
Larval hindgut	396 ± 40	4 of 4	1.08	None
Larval fat body	96 ± 13	4 of 4	0.30	Down
Larval trachea	216 ± 16	4 of 4	0.59	Down
Larval carcass	300 ± 38	4 of 4	0.82	None
S2 cells (growing)	211 ± 5	4 of 4	0.58	Down
Whole fly	368 ± 27	4 of 4

Looking for CG5037-RA. 1 entries matched from 18771, in 0 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720