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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5072-RC through 18771 annotations produced 1 hits

Protein kinase-like 53C (Cdk4):

Annotation Number : CG5072
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0016131
Gbrowse : chr2R:12466980-12472953 (+) // 100.0 //
Probeset : 1639347_s_at
Accessions : protein= NP_477196; /// NP_725594; /// NP_725595;, nucleotide= NM_057848; /// NM_166184; /// NM_166185;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0016131.
Homophila reports that CG5072 is a close match (8e-11) to human gene AUTS9;MET (NP_000236), a gene associated with Hepatocellular carcinoma, childhood type, 114550 (3);Renal cell carcinoma, papillary, familial and sporadic, 605074 (3);{Autism, suseptibility to, 9}, 611015 (3).
BioGrid reports that CG5072 interacts with CG9096 CG9415 CG9096 CG9096 CG9096 CG9096 CG9096 CG9096 CG9096 CG9096 CG7413 CG7413 CG6147 CG6147 CG6975 CG6975 CG32042 CG1871 CG14119 CG7296 CG18806 CG15676 CG15861 CG2948 CG5352 CG5708 CG11182 CG6235 CG7281 CG11138 CG2944 CG12116 CG13806 CG32139 CG7405 CG7980 CG7948 CG11525 CG13344 CG5731 CG15218 CG3850 CG10308 CG1034 CG31679 CG18332 CG5390 CG31811 CG8591 CG4878 CG3938 CG3193 CG17309 CG11849 CG1106 CG13900 CG17964 CG32169 CG5650 CG32045 CG5568 CG2865 CG11963 CG9984 CG2189 CG8823 CG5009 CG11486 CG1765 CG6923 CG7922 CG12323 CG6985 CG9868 CG18745 CG31160 CG5714 CG11652 CG14864 CG4269 CG32505 CG9096 CG4257 CG9096 CG8181 .
TRiP has 2 RNAi stocks for FBgn0016131 available for purchase.
VDRC has 2 RNAi stocks for FBgn0016131 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain17 20 of 4 0.20Down
Head69 54 of 4 0.60Down
Eye51 14 of 4 0.46Down
Thoracicoabdominal ganglion25 22 of 4 0.20Down
Salivary gland15 70 of 4 0.14Down
Crop40 34 of 4 0.40Down
Midgut44 14 of 4 0.40Down
Tubule12 11 of 4 0.10Down
Hindgut29 14 of 4 0.30Down
Heart23 24 of 4 0.21Down
Fat body53 24 of 4 0.48Down
Ovary239 74 of 4 2.10Up
Testis8 01 of 4 0.10Down
Male accessory glands15 20 of 4 0.10Down
Virgin spermatheca22 22 of 4 0.20Down
Mated spermatheca31 12 of 4 0.28Down
Adult carcass47 44 of 4 0.40Down
Larval CNS115 164 of 4 1.03None
Larval Salivary gland112 144 of 4 1.00None
Larval midgut64 64 of 4 0.58Down
Larval tubule27 24 of 4 0.20Down
Larval hindgut87 24 of 4 0.78None
Larval fat body9 31 of 4 0.10Down
Larval trachea152 104 of 4 1.36Up
Larval carcass127 84 of 4 1.13None
S2 cells (growing)172 44 of 4 1.54Up
Whole fly112 94 of 4

Looking for CG5072-RC. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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