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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5249-RA through 18771 annotations produced 1 hits

Blimp-1 (Blimp-1):

Annotation Number : CG5249
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0035625
Gbrowse : chr3L:5624082-5642042 (+) // 99.84 //
Probeset : 1632541_at
Accessions : protein= NP_647982;, nucleotide= NM_139725;
Pathway : open tracheal system // inferred from mutant phenotype"
Interpro : 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay
FlyMine data for FBgn0035625.
BDGP gene expression has embryonic in situ data for CG5249: 40 pix of staining in 26 body parts.
Homophila reports that CG5249 is a close match (5e-11) to human gene AITD3;ZFAT1;ZNF406 (NP_001025110), a gene associated with {Autoimmune thyroid disease, susceptibility to, 3}, 608175 (3).
TRiP has 1 RNAi stocks for FBgn0035625 available for purchase.
VDRC has 3 RNAi stocks for FBgn0035625 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain167 44 of 4 4.10Up
Head78 84 of 4 1.90Up
Eye192 134 of 4 4.76Up
Thoracicoabdominal ganglion210 54 of 4 5.20Up
Salivary gland77 181 of 4 1.91None
Crop158 64 of 4 3.90Up
Midgut57 54 of 4 1.40Up
Tubule37 23 of 4 0.90None
Hindgut109 44 of 4 2.70Up
Heart141 134 of 4 3.51Up
Fat body109 94 of 4 2.71Up
Ovary7 00 of 4 0.20Down
Testis9 11 of 4 0.20Down
Male accessory glands66 74 of 4 1.70Up
Virgin spermatheca142 134 of 4 3.53Up
Mated spermatheca112 94 of 4 2.77Up
Adult carcass100 174 of 4 2.50Up
Larval CNS6 10 of 4 0.17Down
Larval Salivary gland6 20 of 4 0.15Down
Larval midgut12 40 of 4 0.30Down
Larval tubule7 20 of 4 0.20Down
Larval hindgut51 64 of 4 1.28None
Larval fat body10 20 of 4 0.30Down
Larval trachea61 54 of 4 1.52Up
Larval carcass25 51 of 4 0.64None
S2 cells (growing)11 30 of 4 0.29Down
Whole fly40 44 of 4

Looking for CG5249-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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