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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG5367-RA through 18771 annotations produced 1 hits



(CG5367):

Annotation Number : CG5367
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032228
Gbrowse : chr2L:10354809-10356276 (-) // 100.0 //
Probeset : 1635940_at
Accessions : protein= NP_609387;, nucleotide= NM_135543;
Interpro : 0004197 // cysteine-type endopeptidase activity // inferred from sequence or structural similarity /// 0004197 // cystei
FlyMine data for FBgn0032228.
Homophila reports that CG5367 is a close match (3e-24) to human gene CPPI;CTSC;HMS;JPD;PALS;PLS (NP_001805), a gene associated with Haim-Munk syndrome, 245010 (3);Papillon-Lefevre syndrome, 245000 (3);Periodontitis, juvenile, 170650 (3).
VDRC has 2 RNAi stocks for FBgn0032228 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain5 ± 10 of 4 0.20Down
Head11 ± 11 of 4 0.30Down
Eye3 ± 00 of 4 0.09Down
Thoracicoabdominal ganglion6 ± 10 of 4 0.20Down
Salivary gland11 ± 20 of 4 0.35Down
Crop10 ± 21 of 4 0.30Down
Midgut8 ± 10 of 4 0.30Down
Tubule4 ± 00 of 4 0.10Down
Hindgut9 ± 12 of 4 0.30Down
Heart3 ± 10 of 4 0.10Down
Fat body16 ± 10 of 4 0.49Down
Ovary52 ± 44 of 4 1.60Up
Testis8 ± 14 of 4 0.30Down
Male accessory glands9 ± 30 of 4 0.30Down
Virgin spermatheca6 ± 10 of 4 0.18Down
Mated spermatheca6 ± 10 of 4 0.18Down
Adult carcass7 ± 20 of 4 0.20Down
Larval CNS6 ± 13 of 4 0.21Down
Larval Salivary gland14 ± 23 of 4 0.44Down
Larval midgut13 ± 10 of 4 0.40Down
Larval tubule5 ± 20 of 4 0.20Down
Larval hindgut9 ± 11 of 4 0.28Down
Larval fat body12 ± 20 of 4 0.40Down
Larval trachea2 ± 10 of 4 0.07Down
Larval carcass5 ± 10 of 4 0.18Down
S2 cells (growing)8 ± 11 of 4 0.26Down
Whole fly33 ± 34 of 4

Looking for CG5367-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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