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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5389-RA through 18771 annotations produced 1 hits

ATP synthase Beta chain (CG5389):

Annotation Number : CG5389
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0036568
Gbrowse : chr3L:16090933-16093190 (+) // 100.0 //
Probeset : 1640920_at
Accessions : protein= NP_648836;, nucleotide= NM_140579;
Pathway : "0000275 // mitochondrial proton-transporting ATP synthase complex
Interpro : catalytic core F(1) // inferred from sequence or structural similarity /// 0005811 // lipid particle // inferred from d
FlyMine data for FBgn0036568.
BDGP gene expression has embryonic in situ data for CG5389: 8 pix of staining in 1 body parts.
Homophila reports that CG5389 is a close match (1e-19) to human gene ATP6B1;VPP3 (NP_001683), a gene associated with Renal tubular acidosis with deafness, 267300 (3).
VDRC has 3 RNAi stocks for FBgn0036568 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain6 00 of 4 0.20Down
Head9 10 of 4 0.30Down
Eye4 11 of 4 0.16Down
Thoracicoabdominal ganglion7 10 of 4 0.30Down
Salivary gland22 70 of 4 0.77None
Crop9 10 of 4 0.30Down
Midgut14 20 of 4 0.50Down
Tubule9 01 of 4 0.30Down
Hindgut14 22 of 4 0.50Down
Heart3 00 of 4 0.12Down
Fat body18 61 of 4 0.62Down
Ovary6 11 of 4 0.20Down
Testis209 124 of 4 7.10Up
Male accessory glands10 10 of 4 0.40Down
Virgin spermatheca9 20 of 4 0.32Down
Mated spermatheca11 10 of 4 0.40Down
Adult carcass24 22 of 4 0.80None
Larval CNS5 11 of 4 0.20Down
Larval Salivary gland12 11 of 4 0.41Down
Larval midgut19 04 of 4 0.65Down
Larval tubule8 10 of 4 0.30Down
Larval hindgut10 13 of 4 0.36Down
Larval fat body59 143 of 4 2.00None
Larval trachea2 20 of 4 0.09Down
Larval carcass6 20 of 4 0.22Down
S2 cells (growing)6 20 of 4 0.23Down
Whole fly29 04 of 4

Looking for CG5389-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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