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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG5409-RA through 18771 annotations produced 1 hits



Actin-related protein 53D (Arp53D):

Annotation Number : CG5409
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011743
Gbrowse : chr2R:12661924-12663055 (+) // 100.0 //
Probeset : 1636039_at
Accessions : protein= NP_477037;, nucleotide= NM_057689;
Pathway : 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic anno
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskelet
FlyMine data for FBgn0011743.
Homophila reports that CG5409 is a close match (6e-144) to human gene ACTA1;ASMA;CFTD1;NEM1;NEM3 (NP_001091), a gene associated with Myopathy, actin, congenital, with cores (3);Myopathy, actin, congenital, with excess of thin myofilaments, 161800 (3);Myopathy, congenital, with fiber-type disporportion 1, 255310 (3);Myopathy, nemaline, 3, 161800 (3).
VDRC has 3 RNAi stocks for FBgn0011743 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain4 ± 00 of 4 0.10Down
Head2 ± 00 of 4 0.00Down
Eye2 ± 00 of 4 0.04Down
Thoracicoabdominal ganglion0 ± 00 of 4 0.00Down
Salivary gland11 ± 41 of 4 0.18Down
Crop3 ± 10 of 4 0.00Down
Midgut9 ± 10 of 4 0.10Down
Tubule5 ± 00 of 4 0.10Down
Hindgut2 ± 00 of 4 0.00Down
Heart1 ± 00 of 4 0.02Down
Fat body2 ± 10 of 4 0.04Down
Ovary2 ± 00 of 4 0.00Down
Testis930 ± 204 of 414.20Up
Male accessory glands3 ± 10 of 4 0.10Down
Virgin spermatheca2 ± 00 of 4 0.04Down
Mated spermatheca3 ± 10 of 4 0.06Down
Adult carcass10 ± 12 of 4 0.20Down
Larval CNS4 ± 31 of 4 0.07Down
Larval Salivary gland3 ± 10 of 4 0.05Down
Larval midgut4 ± 10 of 4 0.07Down
Larval tubule4 ± 11 of 4 0.10Down
Larval hindgut3 ± 00 of 4 0.05Down
Larval fat body219 ± 1154 of 4 3.40None
Larval trachea6 ± 62 of 4 0.11Down
Larval carcass3 ± 10 of 4 0.06Down
S2 cells (growing)2 ± 10 of 4 0.04Down
Whole fly65 ± 24 of 4

Looking for CG5409-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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