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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG5603-RA through 18771 annotations produced 1 hits



cylindromatosis (CYLD):

Annotation Number : CG5603
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032210
Gbrowse : chr2L:10296387-10299827 (-) // 100.0 //
Probeset : 1625543_s_at
Accessions : protein= NP_609371; /// NP_723554; /// NP_723555; /// NP_723556; /// NP_723557;, nucleotide= NM_135527; /// NM_164909; /// NM_164910; /// NM_164911; /// NM_164912;
Pathway : 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or stru
Interpro : 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarit
FlyMine data for FBgn0032210.
Homophila reports that CG5603 is a close match (3e-91) to human gene CDMT;CYLD1;EAC;MFT1 (NP_056062), a gene associated with Brooke-Spiegler syndrome, 605041 (3);Cylindromatosis, familial, 132700 (3);Trichoepithelioma, multiple familial, 1, 601606 (3).
TRiP has 2 RNAi stocks for FBgn0032210 available for purchase.
VDRC has 2 RNAi stocks for FBgn0032210 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain195 ± 14 of 4 1.90Up
Head124 ± 64 of 4 1.20Up
Eye114 ± 34 of 4 1.14None
Thoracicoabdominal ganglion190 ± 34 of 4 1.90Up
Salivary gland166 ± 94 of 4 1.65Up
Crop168 ± 54 of 4 1.70Up
Midgut108 ± 44 of 4 1.10None
Tubule77 ± 34 of 4 0.80Down
Hindgut136 ± 44 of 4 1.40Up
Heart69 ± 24 of 4 0.69Down
Fat body60 ± 34 of 4 0.60Down
Ovary67 ± 14 of 4 0.70Down
Testis617 ± 374 of 4 6.10Up
Male accessory glands74 ± 44 of 4 0.70Down
Virgin spermatheca44 ± 24 of 4 0.45Down
Mated spermatheca41 ± 24 of 4 0.41Down
Adult carcass84 ± 14 of 4 0.80Down
Larval CNS78 ± 34 of 4 0.78Down
Larval Salivary gland85 ± 74 of 4 0.85None
Larval midgut89 ± 14 of 4 0.89None
Larval tubule148 ± 14 of 4 1.50Up
Larval hindgut85 ± 14 of 4 0.84Down
Larval fat body153 ± 264 of 4 1.50None
Larval trachea67 ± 54 of 4 0.67Down
Larval carcass64 ± 74 of 4 0.64Down
S2 cells (growing)132 ± 44 of 4 1.32Up
Whole fly100 ± 44 of 4

Looking for CG5603-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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