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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5686-RA through 18771 annotations produced 1 hits

flipper (chico):

Annotation Number : CG5686
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0024248
Gbrowse : chr2L:10242509-10247064 (-) // 100.0 //
Probeset : 1631374_at
Accessions : protein= NP_723540;, nucleotide= NM_164899;
Pathway : open tracheal system // inferred from mutant phenotype /// 0040008 // regulation of growth // inferred from electronic
Interpro : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence
FlyMine data for FBgn0024248.
Homophila reports that CG5686 is a close match (7e-30) to human gene IRS2 (NP_003740), a gene associated with {{Diabetes mellitus, noninsulin-dependent}, 125853 (3).
BioGrid reports that CG5686 interacts with CG18402 CG4141 CG5671 CG5671 CG17870 CG31196 CG18402 .
TRiP has 3 RNAi stocks for FBgn0024248 available for purchase.
VDRC has 3 RNAi stocks for FBgn0024248 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain263 114 of 4 1.90Up
Head211 124 of 4 1.50Up
Eye170 124 of 4 1.23None
Thoracicoabdominal ganglion214 94 of 4 1.50Up
Salivary gland267 94 of 4 1.93Up
Crop272 54 of 4 2.00Up
Midgut142 34 of 4 1.00None
Tubule217 84 of 4 1.60Up
Hindgut166 54 of 4 1.20Up
Heart188 84 of 4 1.36Up
Fat body205 84 of 4 1.48Up
Ovary209 34 of 4 1.50Up
Testis40 14 of 4 0.30Down
Male accessory glands232 134 of 4 1.70Up
Virgin spermatheca186 24 of 4 1.34Up
Mated spermatheca185 94 of 4 1.33Up
Adult carcass227 174 of 4 1.60Up
Larval CNS168 54 of 4 1.21Up
Larval Salivary gland157 54 of 4 1.13None
Larval midgut131 124 of 4 0.95None
Larval tubule190 114 of 4 1.40Up
Larval hindgut140 64 of 4 1.01None
Larval fat body175 64 of 4 1.30Up
Larval trachea188 224 of 4 1.36Up
Larval carcass187 64 of 4 1.35Up
S2 cells (growing)167 34 of 4 1.21Up
Whole fly138 74 of 4

Looking for CG5686-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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