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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5731-RA through 18771 annotations produced 1 hits


Annotation Number : CG5731
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032192
Gbrowse : chr2L:10207081-10209721 (-) // 100.0 //
Probeset : 1635163_at
Accessions : protein= NP_609354;, nucleotide= NM_135510;
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity
FlyMine data for FBgn0032192.
Homophila reports that CG5731 is a close match (6e-113) to human gene GLA (NP_000160), a gene associated with Fabry disease, 301500 (3);Fabry disease, cardiac variant, 301500 (3).
BioGrid reports that CG5731 interacts with CG6416 .
VDRC has 2 RNAi stocks for FBgn0032192 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain7 13 of 4 0.30Down
Head28 24 of 4 1.20None
Eye16 14 of 4 0.70Down
Thoracicoabdominal ganglion5 11 of 4 0.20Down
Salivary gland14 20 of 4 0.60Down
Crop7 01 of 4 0.30Down
Midgut6 12 of 4 0.30Down
Tubule6 01 of 4 0.30Down
Hindgut3 11 of 4 0.20Down
Heart7 03 of 4 0.33Down
Fat body11 43 of 4 0.46Down
Ovary4 11 of 4 0.20Down
Testis10 14 of 4 0.40Down
Male accessory glands2358 704 of 499.00Up
Virgin spermatheca11 14 of 4 0.50Down
Mated spermatheca13 14 of 4 0.58Down
Adult carcass29 24 of 4 1.30None
Larval CNS64 94 of 4 2.69Up
Larval Salivary gland16 24 of 4 0.69Down
Larval midgut12 13 of 4 0.51Down
Larval tubule6 10 of 4 0.30Down
Larval hindgut18 04 of 4 0.76Down
Larval fat body14 22 of 4 0.60Down
Larval trachea174 524 of 4 7.33Up
Larval carcass117 74 of 4 4.92Up
S2 cells (growing)34 44 of 4 1.44None
Whole fly23 14 of 4

Looking for CG5731-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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