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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5848-RC through 18771 annotations produced 1 hits

chr2L:16314192-16325655 (-) // 99.79 // (cactus):

Annotation Number : CG5848
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1629899_at
Accessions : protein= , nucleotide= NP_476942; /// NP_476943; /// NP_723960; /// NP_995721;
Pathway : "0006911 // phagocytosis
Interpro : engulfment // inferred from mutant phenotype /// 0006952 // defense response // non-traceable author statement /// 0006
FlyMine data for full length.
Homophila reports that CG5848 is a close match (5e-11) to human gene ANK1;SPH2 (NP_065209), a gene associated with Spherocytosis-2 (3).
BioGrid reports that CG5848 interacts with CG6203 CG6357 CG6667 CG6416 CG7264 CG7352 CG7856 CG8417 CG8925 CG9925 CG7744 CG8457 CG10079 CG5490 CG5490 CG1676 CG6667 CG6667 CG4920 CG4920 CG4920 CG4920 CG4920 CG4920 CG8205 CG17610 CG5974 CG9224 CG6134 CG6134 CG6134 CG6134 CG6134 CG6134 CG10520 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain124 34 of 4 2.60Up
Head72 44 of 4 1.50Up
Eye132 114 of 4 2.74Up
Thoracicoabdominal ganglion90 34 of 4 1.90Up
Salivary gland59 64 of 4 1.22None
Crop532 194 of 411.00Up
Midgut29 14 of 4 0.60Down
Tubule54 34 of 4 1.10Up
Hindgut127 74 of 4 2.60Up
Heart155 144 of 4 3.21Up
Fat body54 74 of 4 1.12None
Ovary41 14 of 4 0.80None
Testis61 34 of 4 1.30None
Male accessory glands36 14 of 4 0.80Down
Virgin spermatheca108 144 of 4 2.24Up
Mated spermatheca101 64 of 4 2.09Up
Adult carcass65 34 of 4 1.40Up
Larval CNS102 134 of 4 2.11Up
Larval Salivary gland161 164 of 4 3.34Up
Larval midgut25 34 of 4 0.53Down
Larval tubule103 114 of 4 2.10Up
Larval hindgut101 44 of 4 2.10Up
Larval fat body72 84 of 4 1.50None
Larval trachea95 24 of 4 1.97Up
Larval carcass223 204 of 4 4.61Up
S2 cells (growing)35 44 of 4 0.74None
Whole fly48 34 of 4

Looking for CG5848-RC. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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